Professor Uday Chand Ghoshal, Professor and Head of the Department of Gastroenterology, SGPGI Lucknow presented a lively talk on the Pathogenesis and Treatment options on IBS on August 7, 2023 in Bose Institute. His talk highlighted the fact that what was once thought of a purely psychogenic disorder, is now established otherwise in which the Gut-Brain axis plays a prominent role. He also emphasised that microbiome dysbiosis plays a major role in IBS pathogenesis and that modulation of diet provides an effective treatment option for these patients.