Nripendranath Mandal

Nripendranath Mandal
Ex-Professor

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Previous appointments:

July 01, 2014 to Present: Professor, Bose Institute, Division of Molecular Medicine, Kolkata-700054, India.

May 14, 2008 to June 30, 2014 (06yrs 01months 18days): Associate Professor, Bose Institute, Division of Molecular Medicine, Kolkata-700054, India.

Dec 22, 2005 to May 13, 2008 (02yrs 04months 23days): Assistant Professor, Bose Institute, Immunotechnology Section, Kolkata-700054, India.

May 14, 1997 to Dec’ 21, 2005 (08yrs 07months 08days): Senior Lecturer, Bose Institute, Immunotechnology Section, Kolkata-700054, India.

June 27, 1994 to August 31, 1996 (02yrs 02months 04 days): Postdoctoral Trainee (NIH), St. Louis University Health Sciences Centre, Dept. of Molecular Microbiology & Immunology, St. Louis, MO 63104, USA.

November 02, 1992 to May 31,1994 (01yrs 06months 29 days):  Research Associate, North Carolina State University, Dept. of Biochemistry, Raleigh, NC 27695, USA

June 30, 1989 to October 31, 1992 (03yrs 04months 01 day): Postdoctoral Associate, Massachusetts Institute of Technology, Dept. of Biology, Cambridge, MA 02139 USA

Research interests:

Themes Of Research Programs:

  • Our primary focus is to address the basic socio-economic problems of some important diseases and to find out inexpensive ways of their solution.
  • To develop new molecular tools or approaches in the field of disease management using the knowledge of modern science and technology.

Objectives Of Research Programs:

  • Development of better & safer natural medicine to combat non-communicable diseases, viz., cancer, diabetes & psoriasis, and amelioration from iron-overload-induced hepatotoxicity.
  • Molecular approaches to control 'White Spot Disease' caused by 'White Spot Syndrome Virus' in marine shrimp aquaculture industry.





Contact:

Address: Division of Molecular Medicine
Centenary Campus
Bose Institute
P-1/12 C.I.T. Scheme VII-M
Kolkata - 700054, India
E-Mail: nripen[at]jcbose.ac.in
Phone: +91-33-25693265

Research:

Research programs are broadly classified into two major field namely Medical Biotechnology and Marine Biotechnology for disease management in human beings as well as marine shrimps.

Medical Biotechnology:

Research output from the Medical Biotechnology program is oriented to develop better and safer medicines using natural resources against various ROS-induced degenerative diseases like cancer, while avoiding the detrimental side effects of conventional therapies involving synthetic drugs. Out of the explored 45 medicinal plants/algae/lichens for potent antioxidant and free radical scavenging efficacies (54 publications), among which 14 are found to be safe and orally-administrable drug candidates to release iron in iron-overload-induced hepatotoxic condition (17 publications). Moreover, among these, 12 have shown in vitro anticancer effects in various cancer cell lines by inducing apoptosis and/or regulation of cell cycle, while being nontoxic to the normal cells (13 publications). For the first time, a lichen extract has been shown to be a source of better and safer drug against breast cancer. Moreover, individual phytochemicals in the extract lost their selective killing, among various cancer and normal cells. This finding has been highly appreciated in 9 different news media. For the first time, 5 pure compounds have been isolated from the bark of Spondias pinnata, among these, 3 compounds (named as SPE3, SPE4 and SPW1) are found to have most potent antioxidants & iron chelating activities as well as anticancer properties. Whereas, SPE2, a novel compound, has shown to have anti-inflammatory activity. Additionally, through multivariate analysis from case control study, has shown that ratio of different apolipoproteins and LDL particle size along with distribution of ABO blood group are potent biomarkers to predict CHD, among Asian Indian population in Eastern part of India. Moreover, the association of E4 allele with CAD and the ratio of anti- to pro-inflammatory cytokine with Acute Myocardial Infarction was also found. From the prevention point of view these observations will play a pivotal role to develop biometric chip for early prediction of CHD (5 publications).






       

Marine Biotechnology:

Aquaculture of marine giant black tiger shrimp Penaeus monodon, a globally profitable industry, has suffered relentless destruction due to White spot disease caused by White Spot Syndrome Virus (WSSV). For the first time, 13 DNA markers (71 bp, 457 bp, 773 bp, 299 bp, 262 bp, 442 bp, 236 bp, 848 bp, 402 bp, 279 bp, 244 bp, 213 bp and 172 bp) have been developed to identify disease resistant/susceptible population of P. monodon from research program of Marine Biotechnology (11 publications, patent taken in 7 countries). Practical utility of these DNA markers have been tested by WSSV challenge experiment and found ~103 fold higher WSSV propagation among disease susceptible whereas greater survivability among disease resistant population in shrimp. All these DNA markers will be useful to develop Specific Pathogen Resistant (SPR) shrimp through Marker Assisted Selection (MAS) of breeding program for disease free shrimp Aquaculture Industry.





Publications:

 

DETAIL PUBLICATIONS:

Total publication: 162 (a) Peer-reviewed Journals: 89; (b) Monograph/Book Published: 4; (c) Patents taken: 7; (d) Sequence submitted at NCBI database: 8; (e) Publication in news media: 9; (f) Abstract Published: 45

(a) PUBLISHED IN PEER-REVIEWED JOURNALS: (TOTAL CITATIONS: 1822 h-index = 20, CUMULATIVE IMPACT FACTOR = 218.787)

 

1.            Ghate, N. B., Chaudhuri, D., Panja, S., Singh, S., Gupta, G., Lee, C. Y. and Mandal, N. (2018) In Vitro Mechanistic Study of the Anti-inflammatory Activity of a Quinoline Isolated from Spondias pinnata bark. Journal of Natural Products (In Press) (Impact factor: 3.88)

2.           Shendge, A. K., Basu, T., Panja, S., Chaudhuri, D. and Mandal, N. (2018) An ellagic acid isolated from Clerodendrum viscosum leaves ameliorates iron-overload induced hepatotoxicity in Swiss albino mice through inhibition of oxidative stress and the apoptotic pathway. Biomedicine & Pharmacotherapy 106: 454–465 (Impact factor: 3.457)

3.            Gupta, G., Das, A., Lee, S. W., Ryu, J. Y., Lee, J., Nagesh, N., Mandal, N. and Lee, C. Y. (2018) BODIPY-based Ir (III) rectangles containing bis-benzimidazole ligands with highly selective toxicity obtained through self-assembly. Journal of Organometallic Chemistry 868: 86 – 94. DOI: 10.1016/j.jorganchem.2018.04.034 (Impact factor: 2.184)

4.            Basu, T., Kumar, B., Shendge, A. K., Panja, S., Chugh, H., Gautam, H. K. and Mandal, N. (2018) An Indian Desert Shrub ‘Hiran Chabba’, Farsetia Hamiltonii Royle, Exhibits Potent Antioxidant and Hepatoprotective Effect Against Iron-Overload Induced Liver Toxicity in Swiss Albino Mice. Current Drug Discoveries and Technologies DOI: 10.2174/1570163815666180418150123 (Impact factor: 4.77)

5.            Basu, T., Panja, S., Shendge, A. K., Das, A. and Mandal, N. (2018) A natural antioxidant, tannic acid mitigates iron‐overload induced hepatotoxicity in Swiss albino mice through ROS regulation. 33:603–618. DOI: 10.1002/tox.22549. Environmental Toxicology (Impact factor: 2.937)

6.            Gupta, G., Das, A., Lee, J., Mandal, N. and Lee, C. Y. (2018) Self-Assembled BODIPY-Based Iridium Metallarectangles: Cytotoxicity and Propensity to Bind Biomolecules. 83: 339–347. DOI: 10.1002/cplu.201800035. ChemPlusChem (Impact factor: 2.797)

7.            Debnath, R. P., Mandal, N. and Rout, J. (2018) Phytochemical screening of macrolichens Acroscyphus sphaerophoroides and Dirinaria consimilis from North East India for antioxidant and antibacterial activities. E-ISSN: 2456-0251, 190-196. Cryptogam Biodiversity and Assessment

8.            Gupta, G., Das, A., Panja, S., Ryu, J. Y., Lee, J., Mandal, N. and Lee, C. Y. (2017) Self-assembly of novel thiophene-based BODIPY Ru(II) rectangles: Potential antiproliferative agents selective against cancer cells. Chemistry A European Journal 23:17199–17203. DOI: 10.1002/chem.201704368 (Impact factor: 5.317)

9.            Shendge, A. K., Basu, T., Sinha, G. P. and Mandal, N. (2017) Assessment of the antioxidant activity and phytochemical analysis of a lichen, Everniastrum cirrhatum (Fr.) Hale ex. Sipman. World Journal of Pharmacy and Pharmaceutical Sciences 6: 1440-1464 DOI: 10.20959/wjpps20179-10056 (Impact factor: 6.647)

10.        Gupta, G., Das, A., Park, K. C., Tron, A., Kim, H., Mun, J., Mandal, N., Chi, K. W., Lee, C. Y. (2017) Self - assembled novel BODIPY - based Pd supramolecules and their cellular localization. Inorganic Chemistry 56:4615–4621 DOI: 10.1021/acs.inorgchem.7b00260 (Impact factor: 4.820)

11.        Basu, T., Mallik, A. and Mandal, N. (2017) Evolving importance of anticancer research using herbal medicine: A scientometric analysis. Scientometrics DOI 10.1007/s11192-016-2223-8 (Impact factor: 2.084)

12.        Basu, T., Panja, S., Ghate, N. B., Chaudhuri, D., and Mandal, N. (2017) Antioxidant and antiproliferative effects of different solvent fractions from Terminalia belerica Roxb. fruit on various cancer cells. Cytotechnology 69:201–216. DOI 10.1007/s10616-016-0051-6 (Impact factor: 1.864)

13.        Shendge, A. K., Basu, T., Chaudhuri, D., Panja, S. and Mandal, N. (2017) In vitro antioxidant and antiproliferative activities of various solvent fractions from Clerodendrum viscosum leaves. Pharmacognosy magazine 13:344-353. DOI 10.4103/pm.pm_395_16 (Impact factor: 1.279)

14.        Chaudhuri, D., Ghate, N. B., Panja, S., Basu, T., Shendge, A. K. and Mandal, N. (2016) Glycoside rich fraction from Spondias pinnata bark ameliorate iron overload induced oxidative stress and hepatic damage in Swiss albino mice. BMC Complementary and Alternative Medicine 16: 262. DOI 10.1186/s12906-016-1244-4 (Impact factor: 2.94)

15.        Chaudhuri, D., Ghate, N. B., Panja, S., and Mandal, N. (2016) Role of phenolics from Spondias pinnata bark in amelioration of iron overload induced hepatic damage in Swiss albino mice. BMC Pharmacology and Toxicology 17: 34. DOI 10.1186/s40360-016-0077-6 (Impact factor: 2.03)

16.        Panja, S., Ghate, N. B. and Mandal, N. (2016) A microalga, Euglena tuba induces apoptosis and suppresses metastasis in human lung and breast carcinoma cells through ROS-mediated regulation of MAPKs. Cancer Cell International 16: 51. DOI: 10.1186/s12935-016-0330-5 (Impact factor: 3.97; Citation: 1)

17.        Gupta, G., Das, A., Ghate, N. B., Kim, T. H., Ryu, J. Y., Lee, J., Mandal, N. and Lee, C. Y. (2016) Novel BODIPY-based Ru (II) and Ir (III) Metalla-rectangles: Cellular Localization of Compounds and Their Antiproliferative Activities. Chemical Communications 52, 4274 – 4277. DOI:10.1039/C6CC00046K (Impact factor: 6.567; Citation: 3)

18.        Ghate, N. B., Das, A., Chaudhuri, D., Panja, S. and Mandal, N. (2016) Sundew plant, a potential source of anti-inflammatory agents, selectively induces G2/M arrest and apoptosis in MCF-7 cells through upregulation of p53 and Bax/Bcl-2 ratio. Nature-Cell Death Discovery 2, 15062. DOI:10.1038/cddiscovery.2015.62 (Citation: 3)

19.        Panja, S., Ghate, N. B., Chaudhuri, D. and Mandal, N. (2016) Antioxidant and free radical scavenging activity of North Eastern edible red alga, Lemania fluviatilis. Proceedings of International Conference on Innovative Approaches in Applied Sciences and Technologies (iCiAsT-2016) February 01-05, 2016

20.        Chaudhuri, D., Ghate, N. B., Panja, S., Das, A. and Mandal, N. (2015) Wild Edible Fruit of Prunus nepalensis Ser. (Steud), a Potential Source of Antioxidants, Ameliorates Iron Overload-Induced Hepatotoxicity and Liver Fibrosis in Mice. PLoS ONE 10(12): e0144280. DOI:10.1371/journal.pone.0144280 (Impact factor: 3.057; Citation: 2)

21.        Chakrabarty, U., Dutta, S., Mallik, A., Mondal, D. and Mandal, N. (2015) Identification and characterisation of microsatellite DNA markers in order to recognise the WSSV susceptible populations of marine giant black tiger shrimp, Penaeus monodon. Veterinary Research 46: 110. DOI: 10.1186/s13567-015-0248-2. (Impact factor: 2.982; Citation: 1)

22.         Ghate, N. B., Chaudhuri, D., Das, A., Panja, S., and Mandal, N. (2015) An Antioxidant Extract of the Insectivorous Plant Drosera burmannii Vahl. Alleviates Iron-Induced Oxidative Stress and Hepatic Injury in Mice. PLoS ONE 10(5): e0128221. DOI:10.1371/journal.pone.0128221 (Impact factor: 3.057; Citation: 4)

23.        Sarkar, R., Hazra, B. and Mandal, N. (2015) Amelioration of iron overload induced liver toxicity by a potent antioxidant and iron chelator, Emblica officinalis Gaertn. Toxicology and Industrial Health 31 (7): 656 – 669. DOI: 10.1177/0748233713483195 (Impact factor: 1.786; Citation: 5)

24.        Das, A., Chaudhuri, D., Ghate, N. B., Panja, S., Chatterjee, A. and Mandal, N. (2015) Protective effect of Clerodendrum colebrookianum leaves against Iron-induced Oxidative Stress and Hepatotoxicity in Swiss albino mice. Indian Journal of Experimental Biology 53:281-291 (Impact factor: 1.35; Citation: 5)

25.        Chaudhuri, D., Ghate N. B., Singh, S.S. and Mandal, N. (2015) Methyl gallate isolated from Spondias pinnata exhibits anticancer activity against human glioblastoma by induction of apoptosis and sustained extracellular signal-regulated kinase 1/2 activation Pharmacognosy magazine 11:269-276. DOI: 10.4103/0973-1296.153078. (Impact factor: 1.279; Citation: 4)

26.        Ghate, N. B., Chaudhuri, D., Panja, S. and Mandal, N. (2015) Nerium indicum leaf alleviates iron-induced oxidative stress and hepatic injury in mice. Pharmaceutical Biology Published online January 22, DOI:10.3109/13880209.2014.959612 (Impact factor: 1.546; Citation: 3)

27.        Hazra, B., Sarkar, R., Chaudhuri, D., Ghate N. B., Panja, S. and Mandal, N. (2015) Attenuation of iron overload induced liver toxicity by Hemidesmus indicus root in Swiss albino mice. International Journal of Pharma and Bio Sciences 6(1): 354-364 (Impact factor: 6.268)

28.        Dutta, S., Chakrabarty, U., Mallik, A. and Mandal, N. (2015) White spot syndrome virus (WSSV) prevalence associated with disease resistance among wild populations of black tiger shrimp, Penaeus monodon (Fabricius). Aquaculture Research. 46: 453–461. DOI: 10.1111/are.12193 (Impact factor: 1.376; Citation: 11)

29.        Ghate, N. B., Chaudhuri, D., Panja, S., Basu Mallik, T., Das, A. and Mandal, N. (2014) Antioxidants from Clerodendrum viscosum leaf play a role in anticancer activity against brain cancer. Journal of Cancer Science & Therapy DOI: http://dx.doi.org/10.4172/1948-5956.S1.034 (Impact factor: 3.09)

30.        Chaudhuri, D., Ghate, N. B., Panja, S., Basu Mallik, T. and Mandal, N. (2014) HPLC screening of Clerodendrum viscosum leaf extract show possible phytochemical responsible for antioxidant and anticancer activities. Journal of Cancer Science & Therapy DOI: http://dx.doi.org/10.4172/1948-5956.S1.038 (Impact factor: 3.09)

31.        Panja, S., Ghate, N. B., Chaudhuri, D. and Mandal, N. (2014) Antioxidant from Indigenous medicinal plants inhibit proliferation of Ascites cancer cell. Journal of Cancer Science & Therapy DOI: http://dx.doi.org/10.4172/1948-5956.S1.038 (Impact factor: 3.09)

32.        Panja, S., Chaudhuri, D., Ghate, N. B. and Mandal, N. (2014) Phytochemical profile of a microalgae Euglena tuba and its hepatoprotective effect against iron-induced liver damage in Swiss albino mice. Journal of Applied Microbiology 117, 1773-1786 DOI:10.1111/jam.12643 (Impact factor: 2.156; Citation: 3)

33.        Chakrabarty, U., Dutta, S., Mallik, A. and Mandal, N. (2014) White spot syndrome virus (WSSV) and prevalence of disease resistance in a commercially cultured population of Penaeus monodon Fabricius, 1798 (Decapoda, Dendrobranchiata). Crustaceana 87 (14), 1593 – 1605 DOI:10.1163/15685403-00003382 (Impact factor: 0.664)

34.        Sarkar, R., Ghate N. B. and Mandal, N. (2014) Antioxidant activity of Tinospora cordifolia extract depends on the solvent system. Journal of Computer Science & Systems Biology 7:5 DOI: http://dx.doi.org/10.4172/0974-7230.S1.008 (Impact factor: 1.59)

35.        Panja, S., Chaudhuri, D., Ghate N. B., Ha, L. M. and Mandal, N. (2014) In vitro assessment of phytochemicals, antioxidant and DNA protective potential of wild edible fruit Elaeagnus latifolia Linn. Fruits 69, 303–314. DOI: 10.1051/fruits/2014019 (Impact factor: 0.904; Citation: 2)

36.        Mallik, A, Chakrabarty, U., Dutta, S.,.Mondal, D. and Mandal, N. (2014) Study on the distribution of disease resistant shrimp identified by DNA markers in respect to WSSV infection in different seasons along the entire East coast of India aiming to prevent white spot disease in Penaeus monodon. Transboundary and Emerging Diseases DOI: 10.1111/tbed.12230 (Impact factor: 2.714; Citation: 2)

37.        Chaudhuri, D., Ghate N. B., Deb, S., Panja, S., Sarkar, R., Rout, J. and Mandal, N. (2014) Assessment of the phytochemical constituents and antioxidant activity of a bloom forming algae Euglena tuba. BMC-Biological Research 47:24 DOI: 10.1186/0717-6287-47-24 (Impact factor: 1.328; Citation: 5)

38.        Biswas, S., Ghosal, P. K. and Mandal, N. (2014) Synergistic effect of anti and pro-inflammatory cytokine genes and their promoter polymorphism with ST-elevation of myocardial infarction. Gene 544(2): 145-151 DOI: 10.1016/j.gene.2014.04.065 (Impact factor: 2.319; Citation: 15)

39.        Chakrabarty, U., Mallik, A., Mondal, D., Dutta, S. and Mandal, N. (2014) Assessment of WSSV prevalence and distribution of disease resistant shrimp among the wild population of Penaeus monodon along the West coast of India. Journal of Invertebrate Pathology 119: 12-18 DOI: 10.1016/j.jip.2014.03.005 (Impact factor: 2.794; Citation: 5)

40.        Mallik, A. and Mandal, N. (2014) Bibliometric analysis of global publication output and collaboration structure study in microRNA research. Scientometrics 98 (3): 2011 – 2037. DOI 10.1007/s11192-013-1128-z (Impact factor: 2.084; Citation: 10       )

41.        Ghate N. B., Hazra, B., Sarkar, R., Chaudhuri, D. and Mandal, N. (2014) Alteration of Bax/Bcl-2 ratio contributes to Terminalia belerica-induced apoptosis in human lung and breast carcinoma. In Vitro Cellular & Developmental Biology - Animal 50 (6): 527-537 DOI: 10.1007/s11626-013-9726-x (Impact factor: 0.971; Citation: 15)

42.        Ghate N. B., Hazra, B., Sarkar, R. and Mandal, N. (2014) In vitro anticancer activity of Spondias pinnata bark on human lung and breast carcinoma. Cytotechnology 66: 209-218 DOI: 10.1007/s10616-013-9553-7 (Impact factor: 1.864; Citation: 17)

43.        Ghate, N. B., Hazra, B., Sarkar, R. and Mandal, N. (2014) Heartwood Extract of Acacia catechu Induces Apoptosis in Human Breast Carcinoma by Altering Bax/Bcl-2 ratio. Pharmacognosy magazine 10: 27-33. DOI: 10.4103/0973-1296.126654. (Impact factor: 1.279; Citation: 17)

44.        Das, A., Chaudhuri, D., Ghate, N. B., Chatterjee, A. and Mandal, N. (2014) Phytochemical Analysis, Antioxidant and Anticancer Potential of Leaf Extracts from Edible Greater Yam, Dioscorea alata L., from North-East India. International Journal of Phytopharmacology 5(2): 109-119 (Impact factor: 1.02; Citation: 3)

45.        Dutta, S., Biswas, S., Mukherjee, K., Chakrabarty, U., Mallik, A. and Mandal, N. (2014) Identification of RAPD-SCAR marker linked to WSSV resistance in populations of giant black tiger shrimp, Penaeus monodon, Fabricius. Journal of Fish Diseases 37(5): 471-480 DOI:10.1111/jfd.12128 (Impact factor: 2.053; Citation: 7)

46.        Ghate, N. B., Chaudhuri, D., Sarkar, R. Sajem, A.L., Panja, S., Rout, J. and Mandal, N. (2013) An antioxidant extract of tropical lichen, Parmotrema reticulatum, induces cell cycle arrest and apoptosis in breast carcinoma cell line MCF-7. PLoS ONE 8(12): e82293. DOI:10.1371/journal.pone.0082293 (Impact factor: 3.057; Citation: 26)

47.        Ha, L. M., Phuong, N. T., Yen, N. T. H., Huong, L. M., and Mandal, N. (2013) Antioxidant activity and chemical constituents from Iris japonica Thunb. Tạp Chi Duợc Liệu 18: 381-385

48.        Biswas, S., Ghoshal, P. K., Halder, B., Ganguly, K., DasBiswas, A. and Mandal, N. (2013) Apolipoproteins AI/B/E gene polymorphism and their plasma levels in patients with coronary artery disease in tertiary care-centre of Eastern India. Indian Heart Journal 65: 658 – 665. DOI: 10.1016/j.ihj.2013.10.003 (Impact factor: 0.464; Citation: 6)

49.        Hazra, B., Sarkar, R., Ghate N. B., Chaudhuri, D. and Mandal, N. (2013) Study on the protective effects of ‘Katha’ (Heartwood extract of Acacia catechu) in iron-overload-induced liver damage. Journal of Environmental Pathology, Toxicology and Oncology DOI: 10.1615/JEnvironPatholToxicolOncol.2013007156 (Impact factor: 1.246; Citation: 3)

50.        Das, A., Chaudhuri, D., Ghate, N. B., Chatterjee, A. and Mandal, N. (2013) Comparative Assessment of Phytochemicals and Antioxidant Potential of Methanolic and Aqueous Extracts of Clerodendrum colebrookianum Walp. leaf from North-East India. International Journal of Pharmacy and Pharmaceutical Sciences 5: 420 – 427 (Impact factor: 0.91; Citation: 3)

51.        Biswas, S.; Ghosal, P. K.; Halder, B. and Mandal, N. (2013) Distribution of ABO Blood Group and Major Cardiovascular Risk Factors with Coronary Heart Disease. BioMed Research International vol. 2013, Article ID 782941 DOI:10.1155/2013/782941 (Impact factor: 2.134; Citation: 15)

52.        Dastidar, P. G., Mallik, A. and Mandal, N. (2013) Contribution of shrimp disease research to the development of the shrimp aquaculture industry: an analysis of the research and innovation structure across the countries. Scientometrics 97 (3): 659 – 674. DOI: 10.1007/s11192-013-0977-9 (Impact factor: 2.084; Citation: 14)

53.        Roy, S., Hazra, B., Mandal, N. and Chaudhuri, T.K. (2013) Assessment of the Antioxidant and Free Radical Scavenging Activities of Methanolic Extract of Diplazium esculentum. International Journal of Food Properties 16(6): 1351-1370, DOI: 10.1080/10942912.2011.587382 (Impact factor: 1.586; Citation: 7)

54.        Dutta S., Chakrabarty U., Mallik A. and Mandal N. (2013) Experimental evidence for WSSV susceptibility linked to a microsatellite DNA marker in Giant Black Tiger Shrimp, Penaeus monodon (Fabricius). Journal of Fish Diseases 36 (6): 593 – 597. DOI:10.1111/jfd.12006 (Impact factor: 2.053, Citation: 9)

55.        Sarkar, R., Hazra, B. and Mandal, N. (2013) Free radical scavenging and hepatoprotective potential of Cajanus cajan leaf extract. Indian Journal of Experimental Biology 51: 165 - 173 (Impact factor: 1.34; Citation: 16)

56.        Hazra, B., Sarkar, R. and Mandal, N. (2013) Spondias pinnata stem bark extract lessens iron overloaded liver toxicity due to hemosiderosis in Swiss albino mice. Annals of Hepatology 12: 123-129 (Impact factor: 2.193, Citation: 5)

57.        Ghate, N. B., Chaudhuri, D. and Mandal, N. (2013) In vitro assessment of Tinospora cordifolia stem for its antioxidant, free radical scavenging and DNA protective potentials. International Journal of Pharma and Bio Sciences 4(1): 373 - 388 (Impact factor: 6.268; Citation: 2)

58.        Dey, P., Chaudhuri, D., Chaudhuri, T.K. and Mandal, N. (2012) Comparative Assessment of The Antioxidant Activity and Free Radical Scavenging Potential of Different Parts of Nerium indicum. International Journal of phytomedicine 4(1): 54-69, DOI: 10.5138/ijpm.v4i1.505 (Impact factor: 1.23; Citation: 19)

59.        Hazra, B., Sarkar, R. and Mandal, N. (2012) Protection of Terminalia belerica Roxb. Against Iron Overload Induced Liver Toxicity: An Account of Its Reducing and Iron Chelating Capacity. American Journal of Pharmacology and Toxicology 7 (3): 109-122, DOI: 10.3844/ajptsp.2012.109.122 (Impact factor: 0.21; Citation: 8)

60.        Chaudhuri, D., Ghate, N. B., Sarkar, R. and Mandal, N. (2012) Phytochemical Analysis and Evaluation of Antioxidant and Free Radical Scavenging Activity of Withania somnifera Root. Asian Journal of Pharmaceutical and Clinical Research 5 (4): 193-199 (Impact factor: 0.51, Citation: 23)

61.        Sarkar, R., Hazra, B. and Mandal, N. (2012) Reducing power and iron chelating property of Terminalia chebula (Retz.) alleviates iron induced liver toxicity in mice. BMC Complementary and Alternative Medicine 12: 144. DOI:10.1186/1472-6882-12-144 (Impact factor: 2.94; Citation: 14)

62.        Sarkar, R. and Mandal, N. (2012) Study of iron chelating and DNA protective activities in hydroalcoholic extract of Indian medicinal plants. International Journal of Pharma and Bio Sciences 3(4): 282-291 (Impact factor: 6.268; Citation: 3)

63.        Sarkar, R., Hazra, B. and Mandal, N. (2012) Hepatoprotective potential of Caesalpinia crista against iron overload induced liver toxicity in mice. Evidence-based Complementary and Alternative Medicine Volume 2012, Article ID 896341, 9 pages DOI:10.1155/2012/896341 (Impact factor: 1.931; Citation: 15)

64.        Dey, P., Chaudhuri, D., Tamang, S., Chaudhuri, T.K. and Mandal, N. (2012) In vitro antioxidant and free radical scavenging potential of Clerodendrum viscosum. International Journal of Pharma and Bio Sciences 3: 454–471 (Impact factor: 6.268; Citation: 13)

65.        Das, A., Chaudhuri, D., Mandal, N. and Chatterjee A. (2012) Study of the antioxidant and the Reactive Oxygen Species Scavenging activity of the edible tuber of “Greater Yam” (Dioscorea alata) from North-East India. Asian Journal of Pharmaceutical and Clinical Research 5(3): 74-84 (Impact factor: 0.51; Citation: 12)

66.        Sarkar, R. and Mandal, N. (2012) Hydroalcoholic extracts of Indian medicinal plants can help in amelioration from oxidative stress through antioxidant properties. Journal of Complementary and Integrative Medicine Volume 9, Issue 1: ISSN (Online), DOI: 10.1515/1553-3840.1583 (Impact factor: 0.429; Citation: 3)

67.        Sarkar, R., Hazra, B. and Mandal, N. (2012) Remediation of iron-overload induced oxidative stress by Caesalpinia crista. Free Radical Biology and Medicine, Volume 53, Supplement 1, September 2012, Page S104, DOI 10.1016/j.freeradbiomed.2012.08.218. (Impact factor: 5.982)

68.        Sarkar, R. and Mandal, N. (2011) In vitro cytotoxic effect of hydroalcoholic extracts of medicinal plants on Ehrlich’s Ascites Carcinoma (EAC). International Journal of phytomedicine 3: 370-380. (Impact factor: 1.23, Citation: 5)

69.        Hazra, B., Sarkar, R., Biswas, S. and Mandal, N. (2011) Antioxidant and iron chelating potential of Pongammia pinnata and its role in preventing free radical induced oxidative damage in plasmid DNA. International Journal of phytomedicine 3: 240-253. (Impact factor: 1.23; Citation: 2)

70.        Hazra, B., Sarkar, R., Biswas, S. and Mandal, N. (2010) Comparative study of the antioxidant and reactive oxygen species scavenging properties in the extracts of the fruits of Terminalia chebula, Terminalia belerica and Emblica officinalis. BMC Complementary and Alternative Medicine 10: 20. DOI:10.1186/1472-6882-10-20 (Impact factor: 2.94; Citation: 167)

71.        Biswas, S., Ghosal, P.K., Mandal, S.C. and Mandal, N. (2010) Relation of anti- to pro-inflammatory cytokine ratios with acute myocardial infarction. The Korean Journal of Internal Medicine 25(1): 44–50. Published online 2010 February 26. DOI: 10.3904/kjim.2010.25.1.44 (Impact factor: 2.03; Citation: 42)

72.        Hazra, B., Sarkar, R., Biswas, S. and Mandal, N. (2010) The Antioxidant, Iron Chelating and DNA Protective Property of 70% Methanolic Extract of “Katha” (Heartwood extract of Acacia catechu) Journal of Complementary and Integrative Medicine 7(1): Article 5, DOI: 10.2202/1553-3840.1335 (Impact factor: 0.429; Citation: 18)

73.        Sarkar, R., Hazra, B., Biswas S. and Mandal, N. (2009) Evaluation of the in vitro antioxidant and iron chelating activity of Gymnema sylvestre Pharmacologyonline 3: 851-865. (Impact factor: 0.37; Citation: 5)

74.        Hazra, B., Sarkar, R., Mandal, S., Biswas, S. and Mandal, N. (2009) Studies on Antioxidant and Antiradical Activities of Dolichos biflorus Seed Extract African Journal of Biotechnology 8 (16): 3927-3933. (Impact factor: 0.57; Citation: 34)

75.        Sarkar, R., Hazra, B., Mandal, S., Biswas, S. and Mandal, N. (2009) Assessment of in vitro antioxidant and free radical scavenging activity of Cajanus cajan Journal of Complementary and Integrative Medicine Volume 6, Issue 1 Article 24, DOI: 10.2202/1553-3840.1248 (Impact factor: 0.429; Citation: 14)

76.        Mandal, S., Hazra, B., Sarkar, R., Biswas, S. and Mandal, N. (2009) Assessment of the antioxidant and reactive oxygen species (ROS) scavenging activity of methanolic extract of Caesalpinia crista leaf Evidence-based Complementary and Alternative Medicine DOI:10.1093/ecam/nep072 (Impact factor: 1.931; Citation: 56)

77.        Mandal, S., Hazra, B., Sarkar, R., Biswas, S. and Mandal, N. (2009) Hemidesmus indicus, an age old plant: study of its in vitro antioxidant and free radical scavenging potentials Pharmacologyonline 1: 604-617 (Impact factor: 0.37; Citation: 4)

78.        Mukherjee, K. and Mandal, N. (2009) A microsatellite DNA Marker developed for identifying disease resistant population of Giant Black Tiger Shrimp (Penaeus monodon). Journal of the World Aquaculture Society 40: 274-280. DOI:10.1111/j.1749-7345.2009.00250.x (Impact factor: 0.665; Citation: 14)

79.        Mukherjee, K. and Mandal, N. (2009) Marine giant black tiger shrimp (Penaeus monodon): Importance of aquaculture, problems and immediate remedies. Science and Culture 75: 192-197 (h index: 2)

80.        Hazra, B., Biswas, S. and Mandal, N. (2008) Antioxidant and free radical scavenging activity of Spondias pinnata. BMC Complementary and Alternative Medicine 8: 63 DOI:10.1186/1472-6882-8-63 (Impact factor: 2.94; Citation: 442)

81.        Biswas, S., Ghosal, P.K., Mandal, S.C. and Mandal, N. (2008) Association of low-density lipoprotein particle size and ratio of different lipoproteins and apolipoproteins with coronary heart disease. Journal of Cardiology 52: 118-126. DOI: 10.1016/j.jjcc.2008.06.005. (Impact factor: 2.405; Citation: 12)

82.        Ghosh, A.K., Jana S., Das, T., Sa, G., Mandal, N. and Ray, P.K. (1999) Protection by Protein A of Apoptotic cell death caused by anti-AIDS drug Zidovudine. Biochemical and Biophysical Research Communications. 264: 601-604 (Impact factor: 2.392; Citation: 16)

83.        Mandal, N., Mangroo, D., Dalluge, J., McCloskey, J.A. and RajBhandary, U.L. (1996) Role of the three consecutive G:C base pairs conserved in the anticodon stem of initiator tRNA in initiation of protein synthesis in Escherichia coli. RNA, 2: 473-482 (Impact factor: 4.94; Citation: 50)

84.        Dyson, M.R., Mandal, N. and RajBhandary, U.L. (1993) Relationship between the structure and function of Escherichia coli initiator tRNA. Biochimie, 75: 1051-1060 DOI: 10.1016/0300-9084(93)90004-C (Impact factor: 3.124; Citation: 6)

85.        Lee, C.P., Mandal, N., Dyson, M.R. and RajBhandary, U.L. (1993). The discriminator base influences tRNA structure at the end of the acceptor stem and possibly its interaction with proteins. Proc. Natl. Acad. Sci., USA, 90: 7149-7152 (Impact factor: 9.423; Citation: 45)

86.        Mandal, N. and Ghosh, R.K. (1993) Structural organization of the transfer RNA gene clusters of cholera phage f149. J. Biosci, 18: 195-205 (Impact factor: 1.419, Citation: 2)

87.        Lee, C.P., Dyson, M.R., Mandal, N., Varshney, U., Bahramian, B. and RajBhandary, U.L. (1992) Striking effects of coupling mutations in the acceptor stem on recognition of tRNAs by Escherichia coli Met-tRNA synthetase and Met-tRNA transformylase. Proc. Natl. Acad. Sci., USA, 89: 9262-9266 DOI: 10.1073/pnas.89.19.9262 (Impact factor: 9.423; Citation: 65)

88.        Mandal, N. and RajBhandary, U.L. (1992) Escherichia coli B lacks one of the two initiator tRNA species present in E. coli K-12. J. Bacteriology, 174: 7827-7830 (Impact factor: 3.38; Citation: 32)

89.        Mandal, N. and Ghosh, R.K. (1988) Characterisation of the phage specific tRNA molecules coded by cholera phage f149. Virology, 166: 583-585. DOI:10.1016/0042-6822(88)90529-6 (Impact factor: 3.200; Citation: 5) 

(b) PUBLISHED REPORT/ MONOGRAPH/ BOOKS:

1.        Das, A., Chaudhuri, D., Sarkar, R., Ghate, N. B., Panja, S., and Mandal, N. (2018) Plants of Indian Traditional Medicine with Antioxidant Activity: In Nutritional Antioxidant Therapies: Treatments and Perspectives, (Edited by Kaïs Hussain Al-Gubory and Ismail Laher). Springer Nature, Springer International Publishing AG, Gewerbestrasse 11, 6330 Cham, Switzerland, pp 27-64. DOI: 10.1007/978-3-319-67625-8

2.        Hazra B., Sarkar R., Biswas S., and Mandal N. (2014) Comparative Study of the Antioxidant and Reactive Oxygen Species Scavenging Properties in the Extracts of the Fruits of Terminalia chebula, Terminalia belerica, and Emblica officinalis:In Recent Advances in Plant-Based, Traditional, and Natural Medicines (Edited by Subramayam Vemulpad and Joanne Jamie). Apple Academic Press, Canada & CRC Press, Taylor & Francis Group, Florida, USA, pp 181-213

3.        Sarkar R. and Mandal N. (2011) In vitro study of the antioxidant, anticancer, iron chelating and DNA protective properties of six medicinal plants, Monograph published in CCRAS, Dept. of AYUSH, Ministry of Health, Govt. of India

4.        Dyson, M.R., Lee, C.P., Mandal, N., Seong, B.L., Varshney, U. and RajBhandary, U.L. (1993) Identity of a prokaryotic initiator tRNA:In The Translational Apparatus, (Edited by K.H. Nierhaus et al.) Plenum Press, New York, pp 23-33. DOI: 10.1007/978-1-4615-2407-6_3 ISBN No: 978-1-4615-2407-6 (Citation: 1) 

(c) PATENTS TAKEN:

Title: A microsatellite DNA marker used for identifying disease resistant populations of Penaeus monodon

Applicants: Department of Biotechnology & Bose Institute

Inventors: Mandal, Nripendranath and Mukherjee, Kuntal

 

Sl. No.

Country

Patent Application No.

Status

1.

Singapore

200605884-6

Filed on March 22, 2006; Granted on September 30, 2009

2.

Malaysia

PI 20064147

Filed on August 14, 2006; Granted on May 31, 2012

3.

Philippines

1-2006-501898

Filed on September 25, 2006; Granted on October 15, 2012

4.

Indonesia

ID P0028730

Filed on March 22, 2006, Granted on July 12, 2011

5.

Vietnam

1-2007-00569

Filed on March 22, 2006, Granted on February 29, 2016

6.

Thailand

0601004023

Filed on August 23, 2006

7.

India

1054/KOL/05

Filed on November 21, 2005

 

(d). SEQUENCE SUBMITTED AT NCBI DATABASE:

1.        Mandal, N. and Mukherjee, K. (2013) DNA markers to identify disease resistant population of Penaeus monodon. Definition: Penaeus monodon clone pm502r RAPD marker genomic sequence. Accession No: KC461828. INV 21-APR-2013

2.        Mandal, N. and Mukherjee, K. (2013) DNA markers to identify disease resistant population of Penaeus monodon. Definition: Penaeus monodon clone pm457rs SCAR marker genomic sequence. Accession No: KC461829. INV 21-APR-2013

3.        Mandal, N., Dutta, S., Chakrabarty, U., and Mallik, A. (2015) A microsatellite DNA marker of 773bp linked to disease resistance in Penaeus monodon. Definition: Penaeus monodon clone pm773m microsatellite DNA marker genomic sequence. Accession No: KP751414.INV 22-JULY 2015.

4.        Mandal, N., Dutta, S., Chakrabarty, U., and Mallik, A. (2015) A microsatellite DNA marker of 299bp linked to disease susceptibility in Penaeus monodon. Definition: Penaeus monodon clone pm299m microsatellite DNA marker genomic sequence. Accession No: KP751415.INV 22-JULY -2015.

5.        Mandal, N., Dutta, S., Chakrabarty, U., and Mallik, A. (2015) A microsatellite DNA marker of 262bp linked to disease susceptibility in Penaeus monodon. Definition: Penaeus monodon clone pm262m microsatellite DNA marker genomic sequence. Accession No: KP751416.INV 22-JULY -2015.

6.        Mandal, N., Chakrabarty, U., Dutta, S., and Mallik, A. (2015) A microsatellite DNA marker of 442bp linked to disease susceptibility in Penaeus monodon. Definition: Penaeus monodon clone pm442m microsatellite DNA marker genomic sequence. Accession No: KP751417.INV 22-JULY -2015.

7.        Mandal, N., Chakrabarty, U., Dutta, S., and Mallik, A. (2015) A microsatellite DNA marker of 236bp linked to disease susceptibility in Penaeus monodon. Definition: Penaeus monodon clone pm236m microsatellite DNA marker genomic sequence. Accession No: KP751418.INV 22-JULY -2015.

8.        Mandal, N., Mallik, A., Dutta, S., Chakrabarty, U., and Mondal, D. (2015) A microsatellite DNA marker of 848bp linked to disease susceptibility in Penaeus monodon. Definition: Penaeus monodon clone pm848m microsatellite DNA marker genomic sequence. Accession No: KP751419.INV 22-JULY -2015.

(e). RESEARCH ACHIEVEMENTS PUBLISHED IN NEWS MEDIA:

1.        The Times of India: http://timesofindia.indiatimes.com/home/science/Northeastern-lichens-may-yield-drug-against-breast-cancer/articleshow/30802564.cms

2.        Zee News: http://zeenews.india.com/news/eco-news/northeastern-lichens-may-yield-drug-against-breast-cancer_913129.html

3.        Northeastnews: http://northeastnews.in/news_details.php?c=23&%20n=4764#.UwsCJoXIYTA

4.        Newkerala: http://www.newkerala.com/news/2014/fullnews-15736.html#.UwsCXIXIYTB

5.        Business standard: http://www.business-standard.com/article/news-ians/northeastern-lichens-may-yield-drug-against-breast-cancer-114022100695_1.html

6.        News reporter: http://newsreporter.in/northeastern-lichens-may-yield-drug-against-breast-cancer-486757

7.        Daijiworld: http://www.daijiworld.com/news/news_disp.asp?n_id=219006

8.        Rediffnews: http://realtime.rediff.com/news/india/Northeastern-lichens-may-yield-drug-against-breast-cancer/14749591549c7816?src=interim_alsoreadimage

9.        IANS: http://ianslive.in/index.php?param=news/Northeastern_lichens_may_yield_drug_against_breast_cancer-413121/Features%20Analyses/35

(f) ABSTRACT PUBLISHED AT INTERNATIONAL/ NATIONAL CONFERENCES/ SYMPOSIUMS:

1.        Panja S., Shendge A. K., Basu T. and Mandal N. (2018) Importance of Lichen to control non-communicable diseases. Abstract in the National Conference on “Current Developments and Next Generation Lichenology” held on January 27 – 28, 2018 at NBRI, Lucknow, India organized by Indian Lichenological Society (ILS) NBRI, Lucknow

2.        Shendge A. K., Panja S., Basu T. and Mandal N. (2018) Bioactive fractions from Parmotrema reticulatum – an alternative source for cancer therapies. Abstract in the National Conference on “Current Developments and Next Generation Lichenology” held on January 27 – 28, 2018 at NBRI, Lucknow, India organized by Indian Lichenological Society (ILS) NBRI, Lucknow

3.        Mandal N., Ghate N. B., Chaudhuri D., Das A., Panja S., Basu T. and Shendge A. K. (2017) Drug development from natural resources: An insectivorous plant, Drosera burmannii, is a source of better medicine to combat breast cancer by altering tumor – microenvironment. Abstract in the “3rd International Conference and Expo on Herbal and Alternative Medicine” held on September 01-02, 2017 at Park Inn by Radisson, London, UK Organized by Allied Academies

4.        Chaudhuri D., Ghate N. B., Panja S. and Mandal N. (2017) Phytochemicals from Spondias pinnata bark alleviate iron overload induced oxidative stress and hepatotoxicity in Swiss albino mice. Abstract in the “3rd International Symposium on Perspective of Cell Signaling and Molecular Medicine” held on January 8-10, 2017 at Bose Institute, Kolkata organized by Division of Molecular Medicine, Bose Institute, Kolkata, India

5.        Panja S., Ghate N. B. and Mandal N. (2017) Apoptotic and anti-metastatic properties of Euglena tuba through the regulation of MAP Kinases. Abstract in the “3rd International Symposium on Perspective of Cell Signaling and Molecular Medicine” held on January 8-10, 2017 at Bose Institute, Kolkata organized by Division of Molecular Medicine, Bose Institute, Kolkata, India

6.        Basu T., Panja S. Ghate N. B., Chaudhuri D. and Mandal N. (2017) Evaluation of the antioxidant and anticancer potentials of polar solvent fractions from Terminalia belerica Roxb. Fruits: A natural source for anticancer drug. Abstract in the “3rd International Symposium on Perspective of Cell Signaling and Molecular Medicine” held on January 8-10, 2017 at Bose Institute, Kolkata organized by Division of Molecular Medicine, Bose Institute, Kolkata, India

7.        Shendge A. K., Basu T., Chaudhuri D., Panja S. and Mandal N. (2017) Antiproliferative activity of antioxidant fractions from Clerodendrum viscosum leaves against various carcinomas: An in vitro study. Abstract in the “3rd International Symposium on Perspective of Cell Signaling and Molecular Medicine” held on January 8-10, 2017 at Bose Institute, Kolkata organized by Division of Molecular Medicine, Bose Institute, Kolkata, India

8.        Mallik A. and Mandal N. (2017) Innovative trends in microRNA research: A scientometric analysis of the global research output. Abstract in the “3rd International Symposium on Perspective of Cell Signaling and Molecular Medicine” held on January 8-10, 2017 at Bose Institute, Kolkata organized by Division of Molecular Medicine, Bose Institute, Kolkata, India

9.        Mondal D., Dutta S., Chakrabarty U., Mallik A. and Mandal N. (2017) Development and characterization of microsatellite DNA markers linked to disease resistance or susceptibility in the population of a marine shrimp, Penaeus monodon Abstract in the “3rd International Symposium on Perspective of Cell Signaling and Molecular Medicine” held on January 8-10, 2017 at Bose Institute, Kolkata organized by Division of Molecular Medicine, Bose Institute, Kolkata, India

10.    Panja S., Ghate N. B., Chaudhuri D. and Mandal N. (2016) Age-old plant, Terminlia belerica, induces apoptosis in lung and breast carcinoma. Abstract in the International Symposium on “Chemical Biology and Drug Discovery & 3rd Annual meeting of Chemical Biology Society (CBS), India”, held on March 1-3, 2016 at Taj Bengal, Kolkata organized by National Institute of Pharmaceutical Education and Research (NIPER), Kolkata; Bose Institute, Kolkata & Chemical Biology Society (CBS), India

11.    Chaudhuri D., Ghate N. B., Panja S., Basu T. and Mandal N. (2016) Anti-glioblastoma potential of methyl gallate isolated from Spondias pinnata bark. Abstract in the International Symposium on “Chemical Biology and Drug Discovery & 3rd Annual meeting of Chemical Biology Society (CBS), India”, held on March 1-3, 2016 at Taj Bengal, Kolkata organized by National Institute of Pharmaceutical Education and Research (NIPER), Kolkata; Bose Institute, Kolkata & Chemical Biology Society (CBS), India

12.    Ghate N. B., Das A., Chaudhuri D., Panja S. and Mandal N. (2016) Insectivorous plant: Source for anti-breast cancer and anti-inflammatory agents. Abstract in the International Symposium on “Chemical Biology and Drug Discovery & 3rd Annual meeting of Chemical Biology Society (CBS), India”, held on March 1-3, 2016 at Taj Bengal, Kolkata organized by National Institute of Pharmaceutical Education and Research (NIPER), Kolkata; Bose Institute, Kolkata & Chemical Biology Society (CBS), India

13.    Chakrabarty U., Dutta S., Mallik A., Mondal D., Mondal V. and Mandal N., (2016) White spot syndrome virus (WSSV) prevalence and distribution of white spot disease (WSD) resistant shrimp among the entire coastal area of india. Abstract in the International Conference on “Aquatic Resources and Sustainable Management”, held on February 17 - 19, 2016 at Science City, Kolkata organized by Central Calcutta Science and Culture Organization for Youth (CCSCOY), Kolkata, India

14.    Mandal N., Dutta S., Chakrabarty U., Mallik A., Mondal D. and Mondal V. (2016) Role of DNA markers to control white spot disease (WSD) in marine shrimp aquaculture. Abstract in the International Conference on “Aquatic Resources and Sustainable Management”, held on February 17 - 19, 2016 at Science City, Kolkata organized by Central Calcutta Science and Culture Organization for Youth (CCSCOY), Kolkata, India

15.    Chaudhuri D., Ghate N. B., Panja S., Das A. and Mandal N. (2016) A wild edible fruit from North East India alleviate iron-induced oxidative stress and hepatotoxicity in mice. Abstract in the International Conference on “Innovative Approaches in Applied Sciences and Technologies”, held on February 01-05, 2016 at Kasetsart University, Bangkok, Thailand organized by Scientific Educational Research Society (SERS), Meerut, India and Kasetsart University, Bangkok,Thailand

16.    Ghate N. B., Chaudhuri D., Das A., Panja S., Basu Mallik T., Shendge A.K. and Mandal N. (2016) Sundew plant: Source for drug against multiple non-communicable diseases. Abstract in the International Conference on “Innovative Approaches in Applied Sciences and Technologies”, held on February 01-05, 2016 at Kasetsart University, Bangkok, Thailand organized by Scientific Educational Research Society (SERS), Meerut, India and Kasetsart University, Bangkok,Thailand

17.    Mandal N. (2016) Role of Biotechnology based research in the field of disease management. Abstract in the National conference on “Bioresources & Bioproducts: Ancient to Recent”, held on January 20, 2016 at Dept. of Zoology, University of Gour Banga, Malda, India organized by Dept. of Zoology, University of Gour Banga, Malda

18.    Ghate N. B., Chaudhuri D. and Mandal N. (2015) A tropical lichen, Parmotrema reticulatum, could be a source for better medicine to combat cancer and inflammatory diseases. Abstract in the National Conference on “Cryptogam Research in India: Progress and Prospects”, held on September 28 – 29, 2015 at NBRI, Lucknow, India organized by Indian Lichenological Society (ILS) NBRI, Lucknow

19.    Ghate N. B., Chaudhuri D., Panja S., Basu Mallik T and Mandal N. (2015) A microalgae, Euglena tuba, ameliorate iron-overload-induced oxidative stress and hepatotoxicity. Abstract in the National Conference on “Cryptogam Research in India: Progress and Prospects”, held on September 28 – 29, 2015 at NBRI, Lucknow, India organized by Indian Lichenological Society (ILS) NBRI, Lucknow

20.    Basu Mallik T., Ghate Baban. N., Chaudhuri D., Panja S. and Mandal N. (2014) Leaf extract of Nerium indicum alleviates iron induced oxidative stress and hepatotoxicity in Swiss-albino mice. Abstract in the “4th International Conference of the World Science Congress”, held on December 16 - 18, 2014 at Jadavpur University, Kolkata organized by Jadavpur University, Kolkata, India

21.    Chakrabarty U., Dutta S., Mallik A., Mondal D. and Mandal N. (2014) Estimation of WSSV infection with distribution of disease resistant population of marine shrimp (Penaeus monodon) along the entire coastal areas of India. Abstract in the “4th International Conference of the World Science Congress”, held on December 16 - 18, 2014 at Jadavpur University, Kolkata organized by Jadavpur University, Kolkata, India

22.    Ghate N. B., Chaudhuri D., Panja S., Basu Mallik T., Das A. and Mandal N. (2014) Antioxidants from Clerodendrum viscosum leaf play a role in anticancer activity against brain cancer. Abstract in the “4th World Congress on Cancer Science & Therapy”, held on October 20 - 22, 2014 at the DoubleTree by Hilton Hotel Chicago-North Shore Conference Center, Skokie, Illinois, Chicago, USA organized by OMICS group Inc., USA

23.    Panja S., Ghate N. B., Chaudhuri D. and Mandal N.  (2014) Antioxidant from Indigenous medicinal plants inhibit proliferation of ascitic cancer cell. Abstract in the “Global Cancer Conference & Medicare Summit”, held on September 15 - 17, 2014 at the Hyderabad International Convention Centre, India organized by OMICS group Inc., USA

24.    Chaudhuri D., Ghate N. B., Panja S., Basu Mallik T. and Mandal N. (2014) HPLC screening of Clerodendrum viscosum leaf extract show possible phytochemical responsible for antioxidant and anticancer activities. Abstract in the “Global Cancer Conference & Medicare Summit”, held on September 15 - 17, 2014 at the Hyderabad International Convention Centre, India organized by OMICS group Inc., USA

25.    Sarkar R., Ghate N. B. and Mandal N. (2014) Antioxidant activity of Tinospora cordifolia extract depends on the solvent system. Abstract in the “2nd International Summit on Integrative Biology”, held on August 04 - 05, 2014 at the Hilton-Chicago/Northbrook, Chicago, USA organized by OMICS group Inc., USA

26.    Mandal N., Sarkar R., Ghate N B., Chaudhuri D., Panja S., Das A. (2014) Present scenario of Medical Biotechnology in India: Importance of Medicinal plants to control iron-overload-induced hepatotoxicity and cancer. Abstract in the National symposium on "Emerging trends in Biotechnology: Present scenario and future dimensions", held on March 29 – 31, 2014 at Utkal University, Odisha organized by Post Graduate Dept. of Biotechnology, Utkal University, Odisha

27.    Mondal D., Dutta S., Chakrabarty U., Mallik A. and Mandal N. (2014) Quantitative estimation of WSSV propagation among disease resistant and disease susceptible population of marine shrimp (Penaeus monodon) Abstract in the National Conference on "Current trends in Life Sciences research and challenges ahead", held on February 28 – March 02, 2014 at Sambalpur University organized by Dept. of Life Sciences, Sambalpur University, Orissa

28.    Dutta S., Chakrabarty U., Mallik A., Mondal D. and Mandal N. (2014) Importance of various DNA markers for the development of specific pathogen resistant (SPR) Penaeus monodon Abstract in the National Conference on "Current trends in Life Sciences research and challenges ahead", held on February 28 – March 02, 2014 at Sambalpur University organized by Dept. of Life Sciences, Sambalpur University, Orissa

29.    Mandal N., Mallik A. (2013) Importance of patents in scientific research: A case study of microRNA research Abstract in the International conference on “Global IPR System and WTO Issues”, held on November 16-17, 2013 at CCS University organized by Dept. of Biotechnology, Ch. Charan Singh University, Meerut (UP) India

30.    Mandal N., Hazra B., Sarkar R., Ghate N. B., Chaudhuri D. (2013) Iron chelation by Terminlia chebula: New remedies from an age-old plant Abstract in the International conference on “Biologically active substances and materials: fundamental and applied problems of production and application”, held on May 27-June 01, 2013 at Crimea, Novy Svet, Ukraine organized by Education-Science Center "Institute of Biology", Taras Shevchenko National University of Kyiv, Ukraine

31.    Mandal N., Chakrabarty U., Dutta S., Khatua S., Mallik A. (2012) Importance of DNA markers linked to disease resistance in marine shrimp (Penaeus monodon) Abstract in the “BIT’s 2nd Annual World Congress of Marine Biotechnology”, held on September 20-23, 2012 organized by BIT Congress Inc., Dalian, China
32.    Sarkar R., Hazra B. and Mandal N. (2012) Remediation of iron-overload induced oxidative stress by Caesalpinia crista. Abstract in the “16th Biennial Meeting of Society for Free Radical Research International (SFRRI 2012)”, held on September 6 - 9, 2012 at the Imperial College, London, UK organized by SFRRI, UK
33.    Sarkar R., Hazra B., Ghate N. B., Chaudhuri D. and Mandal N. (2012) Study of Cajanus cajan leaf extract for antioxidant capacity through ROS scavenging and iron chelating, along with potential anticancer activity Abstract in the “2nd International Symposium on Perspective of Cell Signaling and Molecular Medicine” held on January 8-11, 2012 at Bose Institute, Kolkata organized by Division of Molecular Medicine, Bose Institute, Kolkata, India
34.    Dutta S., Chakrabarty U., Khatua S., Mallik A. and Mandal N. (2012) Importance of DNA markers to identify disease resistant Penaeus monodon for disease free shrimp aquaculture Abstract in the “2nd International Symposium on Perspective of Cell Signaling and Molecular Medicine” held on January 8-11, 2012 at Bose Institute, Kolkata organized by Division of Molecular Medicine, Bose Institute, Kolkata, India
35.    Dastidar P. G., Mallik A. and Mandal N. (2012) Are Academic Research and Innovation policies sufficient to sustain the challenges of Aquaculture industries? An analysis of research dynamics across the countries Abstract in the “22nd Annual Conference of The International Environmetrics Society on Environmental Challenges facing developed and developing countries in a Globalized World: Quantitative approaches to Comprehensive Solutions”, held on January 3-6, 2012 at University of Hyderabad, Gachibowli, Hyderabad, India Organized by CRRAO AIMSCS, UOH Campus and University of Hyderabad, Gachibowli, Hyderabad, India
36.    Dutta S., Chakrabarty U., Khatua S., Mallik A. and Mandal N. (2011) DNA markers linked to disease resistance in shrimp (Penaeus monodon). Abstract in the International symposium on “From innovations in nucleic acids research to regulation of Biological processes”, held on December 17-19, 2011 at IISc, Bangalore organized by Department of Microbiology and Molecular Biology, Indian Institute of Science, Bangalore
37.    Biswas, S., Hazra, B., Sarkar, R., Dutta, S., Khatua, S., Chakraborty, U., Ghate, N., Mallick, A., and Mandal, N. (2011) Importance of Biotechnology to control various diseases in human as well as in aquatic animal. Abstract in Sir J.C. Bose Memorial National Symposium on “Modern Trends in Animal Science Research and Challenges of the Day”, held on March 23, 2011 organized by Department of Zoology and Molecular Biology & Genetics, Presidency University, Kolkata
38.    Mandal, N. (2010). Importance of DNA markers for developing disease free shrimp (Peneaus monodon) aquaculture. Abstract in National Symposium on “Parasite Taxonomy, Biodiversity and Fish Health: Environmental Impact”, held on March 12- 13, 2010 at Andhra University organized by Department of Zoology, Andhra University, Visakhapatnam, Andhra Pradesh
39.    Hazra, B., Sarkar, R., Mandal, S., Biswas, S. and Mandal, N. (2008) Study in a comparative basis of antioxidant capacity, free radical scavenging and iron chelation activities of aqueous extracts of three plants, Terminalia chebula, Terminalia belerica and Emblica officinalis Abstract in International Symposium on “Perspective of Cell Signaling and Molecular Medicine”, held on November 27-29, 2008 at Bose Institute, Kolkata organized by Division of Molecular Medicine, Bose Institute, Kolkata, India
40.    Sengupta, M., Samanta, B., Biswas, S. and Mandal, N. (2008) Prevalence of white spot syndrome virus (WSSV) in Wild and cultured giant black tiger shrimp (Penaeus monodon) in the estuarine and coastal areas of West Bengal, India Abstract in International Symposium on “Perspective of Cell Signaling and Molecular Medicine”, held on November 27-29, 2008 at Bose Institute, Kolkata organized by Division of Molecular Medicine, Bose Institute, Kolkata, India
41.    Mukherjee, K.; Biswas, S.; Hazra, B. and Mandal, N. (2007) Indian traditional medicine to combat cancer and other related disease. Abstract in “2nd International Symposium on Translational Research: Natural Products and Cancer”, held on December 9-12, 2007 at Lonavala, Mumbai, India organized by The University of Texas, M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, BOX 143, Houston, TX 77030, USA
42.    Mukherjee, K. and Mandal, N. (2006). Disease resistant microsatellite DNA marker of Giant black tiger shrimp, Penaeus monodon. Abstract in National Symposium on “Cross-Talk Between Zoology and Technology”, held on November 16- 17, 2006 at University of North Bengal, Siliguri organized by Department of Zoology, University of North Bengal, Siliguri - 734013, West Bengal
43.    Mukherjee, K. and Mandal, N. (2006). Sustainability of disease resistant shrimp (Penaeus monodon) aquaculture. Abstract in the “4th International Symposium on Biocontrol and Biotechnology”,held on November 27- 29, 2006 , at Lady Doak College, Madurai organized by Department of Zoology and Biotechnology, Madurai, Tamil Nadu, India
44.    Mukherjee, K. and Mandal, N. (2006). Disease management of Giant black tiger shrimp Penaeus monodon. Abstract in National Symposium on “Biomedicine in Aquaculture”, held on March 17- 18, 2006 at Centre for Marine Science and Technology, Marina Campus, Rajakkamanglam - 629 502, Kanyakumari District, Tamil Nadu organized by, Manonamiam Sundaranar University

45.    Mandal, N. and Ghosh, R.K. (1988). Studies on the transfer RNA molecules coded by vibrio phage f149. Abstract in “5th annual meeting of The Society of Biological Chemist (India)”, held on New Delhi, India organized by SBC, India
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Recognition:

  • Elected Fellow of SERS – 2015 for outstanding contribution in the field of Cancer Research given by Scientific and Educational Research Society, Meerut, February 01-05, 2016
  • Elected Fellow of FZS – 2014 for outstanding contribution in the field of Molecular Biology and Biotechnology given by The Zoological Society, Kolkata, July 27, 2015
  • Received “RAJIV GANDHI EXCELLENCE AWARD” at a seminar on the occasion of the celebration birthday of former prime minister late Shri Rajiv Gandhi at New Delhi, India organized by India International Friendship Society (IIFS), New Delhi, August 18, 2008
  • Received “BHARAT JYOTI AWARD” in the conference on “Economic Growth and National Integration” at New Delhi, India organized by India International Friendship Society (IIFS), New Delhi, May 31, 2008
  • Received “GLORY OF INDIA GOLD MEDAL” in the conference on “Economic Growth and National Integration” at New Delhi, India organized by International Institute of Success Awareness (IISA), New Delhi, May 31, 2008
  • Received a prestigious “POSTDOCTORAL TRAINING FELLOWSHIP” award by National Institute of Health (NIH), USA, June 27, 1994 to August 31, 1996
  • Received award of CSIR-NET-JRF & SRF, Gov. of India, March 14,1984 to March 31, 1989
  • Life member of Indian Lichenological Society (ILS), India, December 22, 2014
  • Life Member of The Asiatic Society, Kolkata, January 02, 2006
  • Life member of Society of Biological Chemist (SBC), India, January 05, 1998

Teaching:

TEACHING EXPERIENCES:

Teaching experience at PG level: 12 years

  1. Conducted Teaching and Examination on “Fishery Science Course, Unit I & II” as a Visiting Fellow under UGC-Assigned Grant Scheme for 3rd semester M.Sc. (Fishery Science) Students at Vidyasagar University, 03rd – 09th February, 2017 
  2. Conducted Teaching and Examination of a course on “Molecular and Cell Biology” for 4th semester Integrated M.Sc. – Ph.D.(Life Science) at Bose Institute, 2012 – 2016 
  3. Conducted Teaching and Examination of a course on “Advanced Immunology” as a Visiting Fellow under UGC-Special Assistance Program for 4th semester M.Sc. (Zoology) Students at University of North Bengal, 17th – 26th February, 2011; 12th – 21st March, 2012
  4. Conducted Teaching and Examination of a course on “Biochemistry” as a Visiting Professor under UGC-unassigned grant for 3rd semester M.Sc. (Zoology) Students at Guwahati University, 16th – 25th October, 2011
  5. Conducted Teaching and Examination of a course on “Animal Biotechnology and Gene Therapy” as a Guest Teacher for M.Sc (Genetics) Part-II students, University of Calcutta, August 19,  2005 - December 23, 2005; February 01, 2008 - June 30, 2008; March 05, 2010 - June 30, 2010
  6. Conducted Teaching and Examination of a semester course on “Molecular Biology” for M. FSc. Students at CIFE, Mumbai, January 01, 2009 - June 30, 2009
  7. Conducted Teaching and Examination of a course on “Gene Therapy” for M.Sc. (Biotechnology) Students, University of North Bengal, 22-26th March, 2004

Teaching experience at Ph. D. level: 12 years

  1. Conducted Teaching and Examination of a course on “Medical & Animal Biotechnology” as a Co-Ordinator for Ph.D. Students at Bose Institute, 2014 – present
  2. Conducted Teaching and Examination of a course on “Medical Biotechnology” as a Co-Ordinator for Ph.D. Students at Bose Institute, 2002-2006, 2008-2011
  3. Conducted Teaching and Examination of a certificate course on “Sophisticated Instruments used in Biological and Biomedical Research” as a Co-Ordinator for Post M. Sc. Students at Bose Institute, 2000-2001
  4. Conducted Teaching and Examination of a course on “Molecular Biology Technique” as a Co-Ordinator for Ph.D. Students at Bose Institute, 1997-1998

Teaching experience at faculty training program: 04 years

  1. Delivered a lecture on “Burden & Risk of Non communicable diseases among Asian Indian population: An age old practice for their remedies using traditional medicine” as a Resource Person at the Refresher Course in Behavioural Sciences on the theme ‘Theories and Practices in Anthropology and other Behavioural Sciences’ during February 02 - 22, 2017 organized by Dept. of Anthropology, University of Calcutta, February 17, 2017
  2. Delivered four (4) lectures on “Stress Response and Non-Communicable Disease in Human” & “Stress Response and Viral Disease in Marine Shrimp” as a Resource Person at the Refresher Course - Life Sciences entitled “Molecular Approaches of Stress Response in Living Organisms” during October 10 - 30, 2014 organized by UGC – Academic Staff College, Sambalpur University, Odisha, October 20 & 21, 2014
  3. Delivered four (4) lectures on “Micro RNA: A magic molecule in the living world” & “Herbal medicine and its importance in 21st century” as a Resource Person at the AICTE supported Staff development programme entitled “Molecules of Living things” during June 19 – July 03, 2006 organized by Periyar Maniammai College of Technology for Women, Periyar Nagar, Villam, Thanjavur-613403, Tamil Nadu, June 20 & 21, 2006
  4. Delivered a lectures on “Biotechnology in 21st century” as a Resource Person for UGC-NAAC programme organized by Ramananda College, Bishnupur, Burduan University, March 12, 2004


Present:

Image Name Designation Department Campus Contact number Email

Former:

RESEARCH GUIDANCE EXPERIENCES:

Research Guidance/No. of Ph.Ds. awarded:

(1)            Srikanta Jana, Ph. D. awarded May 07, 2003, JU

(2)            Kuntal Mukherjee, Ph. D. awarded November 12, 2008, JU

(3)            Santanu Biswas, Ph. D. awarded February 17, 2011, JU

(4)            Bibhabasu Hazra, Ph. D. awarded June 27, 2013, JU

(5)            Rhitajit Sarkar, Ph. D. awarded January 02, 2015, CU

(6)            Sourav Dutta, Ph. D. awarded July 08, 2016, CU

(7)            Nikhil Baban Ghate, Ph. D. awarded July 27, 2016, CU

(8)            Usri Chakrabarty, Ph. D. awarded August 08, 2016, CU

(9)            Ajoy Mallik, Ph. D. awarded October 25, 2016, CU

(10)         Dipankar Chaudhuri Ph. D. awarded November 25, 2016, CU

(11)          Sourav Panja registered for Ph. D. June 17, 2015, CU

(12)          Tapasree Basu registered for Ph. D. June 17, 2015, CU

(13)          Debabrata Mondal registered for Ph. D. July 22, 2016, CU

(14)          Shendge Anil Khushalrao registered for Ph. D. July 10, 2017, CU

Post-doctoral trainee:

(1)            Dr. Abhishek Das, DBT-PD Fellow, 2014 - Present

(2)            Dr. Santanu Biswas, DBT-PD Fellow, 2012

(3)            Dr. Arnab Ghosh, DBT-PD Fellow 2004

(4)            Dr. Eliza Chakraborty, DBT-PD Fellow 1998-2000

(5)            Dr. Selvamani Vijaylingam, DBT-PD Fellow 1999-2000

Post graduate level:

(1)            Ms. Humaira Ilyas, M. Sc. (Life Science), BI, 2015

(2)            Mr. Mrinmoy Sinha, M.Sc. (Molecular Biology & Biotechnology), Kalyani U, 2014

(3)            Mr. Himangshu Pathak, B.Tech. (Biotechnology), Nagaland U, 2011

(4)            Mr. Devmurari Prakashkumar Ashokbhai, M. Sc. (Microbiology), Sarder Patel U, 2009

(5)            Mr. Paul Tseng, M. Sc. (Biotechnology), Allahbad Agriculture U, 2007

(6)            Mr. Dias Arthur Gonsalino, M. Sc. (Biotechnology), Allahbad Agriculture U, 2007

(7)            Mr. Pavan Kumar Annam, M.F.Sc. (Fish Genetics and Biotech), CIFE, 2005-2006

(8)            Mr. M. Sekar, M. F. Sc. (Fish Genetics and Biotech), CIFE, 2005-2006

(9)            Mr. Deborshi De, M. Sc. (Biochemistry),Calcutta U, 2006

(10)         Mr. Suny Das, M. Sc. (Genetics), Calcutta U, 2005

(11)         Mr. Subha Das, M. Sc. (Genetics), Calcutta U, 2004

(12)         Mr. Kuladeep Jana, M. Sc. (Physiology), Vidyasagar U, 1998

Group News:

RESEARCH HIGHLIGHTS:

The goal of scientific work should be devoted for the betterment of common people and if the knowledge of science is not useful for the people of grass root level then it is of no use. All of our research works are based on this important mission. Currently, our research programs are in the field of Medical Biotechnology for disease management in human beings, for the welfare of the people with the help of modern science and technology. We have achieved a number of important observations using various natural resources also including those collected from North-East India, which definitely have the potential for the development of promising herbal based medicine to control various non-communicable diseases including cancer, thalassemia, diabetes and psoriasis.

Aquaculture of marine giant black tiger shrimp Penaeus monodon, a globally profitable industry, has suffered relentless destruction due to White spot disease caused by White Spot Syndrome Virus (WSSV). For the first time, our group has developed thirteen DNA markers to identify disease resistant and disease susceptible population of P. monodon from the research program of Marine Biotechnology. Practical utility of these DNA markers have been tested by WSSV challenge experiment and found ~103 fold higher WSSV propagation among disease susceptible whereas greater survivability among disease resistant population of shrimp. All these DNA markers will be useful to develop Specific Pathogen Resistant (SPR) shrimp through Marker Assisted Selection (MAS) of breeding program for disease free shrimp Aquaculture Industry.