
Anupama Ghosh
Assistant Professor
Anupama Ghosh
Assistant Professor, Division of Plant Biology
PhD: Saha Institute of Nuclear Physics , 2010
Previous appointments:
Post-Doctoral Research Fellow at Department of Organismic Interactions, Max Planck Institute for Terrestrial Microbiology
Research interests:
- Functional studies on secreted effector proteins from different phytopathogenic fungi
- defense mechanisms of host plants against pathogen invasion involving apoplastic proteins
Contact:
Address: |
Division of Plant Biology Centenary Campus Bose Institute P-1/12 C.I.T. Scheme VII-M Kolkata - 700054, India |
E-Mail: | ghosh.anupama[at]jcbose.ac.in |
Phone: | +91-33-25693348 |
Research:
·
Survival
strategies of corn smut fungus Ustilago
maydis during host colonization
Ustilago
maydis is a biotrophic fungus that infects Zea mays. During host colonization the
fungus is exposed to a number of plant defense responses like for instance
elevated levels of reactive oxygen species (ROS) in the vicinity of the
invasion site. Depending upon the compatibility of the pathogen and the host
strain this ROS stimuli can either initiate a cell death response in the pathogen
or could be overcome by the defense responses of the pathogen itself. In this
project we are engaged in dissecting these survival and death pathways of Ustilago maydis during a compatible and
incompatible interaction with the host plant Zea mays.
·
Functional
characterization of U. maydis
effector proteins
Effector proteins are
key factors defining the virulence of a phytopathogenic fungus like Ustilago maydis. In this project we are
engaged in investigating the functions of different groups of secreted effector
proteins from Ustilago maydis in the
context of their role in manipulating host defense responses.
·
Functional
proteomics of rice apoplastic fluid
This project is aimed
to study the apoplastic fluid proteome of rice under conditions of pathogen
invasion. Through this study we are investigating on one hand the in-planta secretome
of different pathogens infecting rice and on the other hand rice secreted
proteins that play crucial roles in defense against pathogen invasion.
Publications:
1. Mukherjee D, Gupta S, Saran N, Datta R, Ghosh A*. Induction of apoptosis-like cell death and clearance of stress induced intracellular protein aggregates: dual roles for Ustilago maydis metacaspase Mca1. Molecular Microbiology 2017, Sep 23, doi: 10.1111/mmi.13848.
2. Ghosh A*, Raha S. Proteases from protozoa and their role in infection. Proteases in physiology and pathology 2017, pp 143-158 (book chapter)
3. Ray D, Ghosh A, Banerjee Mustafi S, Raha S. Plant stress response: HSP70 in the spotlight. Heat shock proteins and plants 2016, pp 123-147 (book chapter)
4.
Ghosh P, Roy A, Hess D, Ghosh A, Das S. Deciphering the Mode of Action of a
Modified Allium sativum Leaf Agglutinin (mASAL), a Potent antifungal Protein on
Rhizoctonia solani. BMC Microbiology
2015; Oct 26;15:237.
5.
Ghosh A*, Raha S.
Molecular and functional characterization of a stress responsive cysteine
protease, EhCP6 from Entamoeba histolytica. Protein Expression and Purification
2015 May;109:55-61. doi:
10.1016/j.pep.2015.02.005.
6. Ghosh A*.
Small heat shock proteins (HSP12, HSP20 and HSP30) play a role in Ustilago maydis pathogenesis. FEMS
Microbiology Letters 2014 Sep 22; doi: 10.1111/1574-6968.12605
7. Djamei
A£, Schipper K£, Rabe F, Ghosh A,
Vincon V, Kahnt J, Osorio S, Tohge T, Fernie AR, Feussner I, Feussner K,
Meinicke P, Stierhof YD, Schwarz H, Macek B, Mann M, Kahmann R. Metabolic
priming by a secreted fungal effector. Nature 2011 Oct 5;
478(7369): 395-8. doi: 10.1038/nature10454.
8. Ghosh AS,
Ray D, Dutta S, Raha S. EhMAPK, the mitogen-activated protein kinase from
Entamoeba histolytica is associated with cell survival. PLoS One 2010 Oct 8;
5(10): e13291. doi: 10.1371/journal.pone.0013291.
9. Ghosh AS,
Dutta S, Raha S. Hydrogen peroxide-induced apoptosis-like cell death in
Entamoeba histolytica. Parasitology International 2010 Jun; 59(2): 166-72. doi:
10.1016/j.parint.2010.01.001. Epub 2010 Jan 15.
10. Dutta S, Sardar A, Ray D, Raha S. Molecular and functional characterization of EhPAK3 a p21 activated kinase from Entamoeba histolytica. Gene 2007 Nov 1;402(1-2):57-67.
£ Contributed equally
* Author for correspondence
Recognition:
- Selected as DST-INSPIRE Faculty by Department of Science and Technology (DST), India, 2013
- Recipient of Postdoctoral Fellowship from Max Planck Society, 2010-2013
- Recipient of Early Career Research Award from SERB, 2018
Teaching:
" Plant Molecular Biology Course " in the Integrated M.Sc. PhD Programme of Bose Institute.
Topics covered:
1. Transport of micro and macro molecules
2. Plant stress signalling during pathogen (bacterial and fungal phytopathogens) invasion
Present:
Image | Name | Designation | Department | Campus | Contact number | |
---|---|---|---|---|---|---|
![]() |
Dibya Mukherjee | SRF | Division of Plant Biology | Centenary | 25693348 | mukherjee.dibya90@gmail.com |
![]() |
Rahul Datta | SRF(I) | Division of Plant Biology | Centenary | 25693348 | rahuldatta638@gmail.com |
![]() |
Subhasish Mukherjee | JRF | Division of Plant Biology | Centenary | 25693348 | s.mukherjee |
![]() |
Udita Acharya | JRF | Division of Plant Biology | Centenary | 25693348 | uditaacharya11 |
Former:
Rahul Datta, JRF (Email: rahuldatta638@gmail.com)
Dibya Mukherjee, JRF (Email: mukherjee.dibya90@gmail.com)
Udita Acharya, JRF (Email: uacharya93@gmail.com)
Subhasish Mukherjee, JRF (Email: mukherjeesubhasish30@gmail.com)
Aroni Mitra, JRF (Email: aronimitra28@gmail.com)
Srimoyee Banerjee, CSIR-RA (srimoyee1717@gmail.com)
Group News:
Best poster award to Dibya Mukherjee in the 10th Conference on Yeast Biology; Model Yeasts to Fungal pathogens held at JNU, New Delhi and Amity University, Gurgaon during 08th to 11th February 2018....