Abhrajyoti Ghosh

Abhrajyoti Ghosh
Associate Professor

Previous appointments:

1. Max Planck Postdoctoral Fellow at Max Planck Institute for Terrestrial Microbiology, Marburg, Germany (2008-2012).

2. Research Associate at Department of Biochemistry, University of Calcutta (2012-2013).

3. DST-Ramanujan Fellow at Department of Biochemistry, Bose Institute (2014-2018).

4. Assistant professor, Department of Biochemistry, Bose Institute (2016-2020).

Research interests:

My laboratory is involved in understanding microbial stress response and adaptation. We use a variety of techniques starting with biochemistry, microbiology, and genomics, for identification & characterization of the molecular players important in the survival of microorganisms in the natural environment. 


Contact:

Address: Biological Sciences
Unified Academic Campus
Bose Institute
EN-80, Sector V
Bidhan Nagar
Kolkata - 700 091, India
E-Mail: abhrajyoti.ghosh[at]jcbose.ac.in
Phone: +91-33-25693284

Research:

Archaeal stress response:

The study of archaea, the third domain of life can provide interesting insights into the evolutionary history of different cellular pieces of machinery and mechanisms across all life forms. One such mechanism of our concern is that of protein translocation across biological membranes in archaea. Our present focus is on the structural and functional analyses of molecules that are central to the archaeal secretion process under different limiting conditions. Since archaea can sustain such extreme limiting conditions, withstanding different kinds of stresses, we also aim to get a thorough idea about the effect of different types of stressors on archaeal cells at the transcriptomic and proteomic levels. We want to study the fate of stress-related proteins under conditions of stress, which includes identification, characterization, and analysis of the mode of regulation of stress-related proteins and their targets. Therefore, the current research in our lab is concerned with understanding the effect of heat stress on archaea in regard to different molecular chaperones. In addition, our recent venture is to study the role of toxin-antitoxin systems in stress adaptation in archaea.

Stress adaptation of environmental microbes:

A changing environment creates conditions that can be stressful for microorganisms. To cope with environmental stress, microbes have a variety of evolutionary adaptations and physiological acclimatization mechanisms. Such adaption and acclimatization strategies allow them to survive and remain metabolically active in the face of environmental stress. However, not all microorganisms are equipped with the necessary arsenals to adapt to the changing environment, and therefore a shift in microbial community composition is often documented under stress conditions. It is believed to be mainly due to a change in ecosystem-level carbon, energy, and nutrient flows that drive alteration in microbial dynamics.

In contrast to conventional strategies of understanding specific organismal responses to environmental stress, our approach aims at developing a more reliable connection between microbial and ecosystem ecology. In our laboratory, we study the diversity, distribution, and function of microorganisms (archaeal and bacteria) in the natural environment. We study microbial structure and function in two unique ecosystems, i.e., the Sundarban mangrove ecosystem and the tea plantation ecosystem of Darjeeling. We adopt genomic and proteomic approaches to find out novel metabolic pathways involved in either heavy metal resistance, antimicrobial resistance, biocatalysis, and novel antimicrobial biosynthesis, etc., in the resident microorganisms. Moreover, we extend our interest in a study of the host (plant)-associated microbiome in these environments. Plants are intimately associated with vast numbers of microorganisms in the rhizosphere. The rhizosphere microbiome is not static, and the microbial community structure in the rhizosphere micro-niche can change in response to stresses and environmental stimuli. Recent studies support that the changes in the rhizosphere microbiome are not merely passive responses of plants but rather, as a consequence of millions of years coevolution, plants likely actively seek cooperation with microbes to fight stresses. We study the rhizosphere microbiome of mangrove plants and tea plants with particular emphasis on plant-growth-promoting rhizobacteria (PGPR).

 

Publications:

Publication from Bose Institute:

A) Archaeal stress response:

Roy, M, Bhakta, K, Bhowmick, A, Gupta, S, Ghosh, A, Ghosh, A*. (2022) Archaeal Hsp14 drives substrate shuttling between small heat shock proteins and thermosome: insights into a novel substrate transfer pathway. FEBS Journal 289(4): 1080-1104  https://doi.org/10.1111/febs.16226 (*Corresponding author)

Gupta, S, Sinha, S, Bhakta, K, Bhowmick, A, Ghosh, A*. (2022) N-terminal helices and A domain of archaeal FtsY facilitate SRP54 binding and the association with cell membrane. bioRxiv 2022.04.13.488184; doi: https://doi.org/10.1101/2022.04.13.488184

Gupta, S, Roy, M, Dey, D, Bhakta, K, Bhowmick, A. Chattopahyay, D, Ghosh, A*. (2021) Archaeal SRP RNA and SRP19 facilitate the assembly of SRP54-FtsY targeting complex. Biochemical and Biophysical Research Communications 566:53-58.

Roy, M, Gupta, S, Patranabis, S, Ghosh, A*. (2018) The oligomeric plasticity of Hsp20 of Sulfolobus acidocaldarius protects environment-induced protein aggregation and membrane destabilization. BBA-Biomembranes 1860(12): 2549-2565.

B) Stress adaptation of environmental microbes:

Mukherji, S, Imchen, M, Mondal, S, Bhattacharyya, A, Siddhartha, B, Kumavath, R, Ghosh, A*. (2022) Anthropogenic impact accelerates antibiotic resistome diversity in the mangrove sediment of Indian Sundarban. Chemosphere  309: 136806


Mukherji, S, Bakshi, U, Ghosh, A*. (2022) Draft genome sequences of hydrocarbon degrading Haloferax sp. AB510, Haladaptatus sp. AB618 and Haladaptatus sp. AB643 isolated from the estuarine sediments of Sundarban mangrove forests, India. 3 Biotech 12: 204. https://doi.org/10.1007/s13205-022-03273-5


Bhattacharyya, C, Imchen, M, Mukherjee, T, Haldar, S, Mondal, S, Mukherji, S, Haldar, A, Kumavath, R, Ghosh, A*. (2022) Rhizosphere impact bacterial community structure in the tea (Camellia sinensis (L.) O. Kuntze.) estates of Darjeeling, India. Environmental Microbiology 24(6): 2716-2731 https://doi.org/10.1111/1462-2920.15874

Bhattacharya C, Banerjee S, Acharya U, Mitra A, Mallick I, Halder A, Haldar S, Ghosh A*, Ghosh A*. (2020) Evaluation of plant growth promotion and induction of antioxidative defense mechanism by rhizobacteria isolated from tea rhizosphere of Darjeeling, India. Scientific Reports 10(1): 15536    (*Corresponding authors) 

Mukherji, S, Ghosh, A, Bhattacharyya, C, Mallick, I, Anish Bhattacharyya, A, Mitra, S, Ghosh, A*. (2020)   Molecular and culture-based surveys of metabolically active hydrocarbon-degrading archaeal communities in Sundarban mangrove sediments. Ecotox Environ Safety 195:110481.

Bhattacharyya, A, Haldar, A, Bhattacharyya, M, Ghosh, A*. (2019) Anthropogenic influence shapes the distribution of antibiotic resistant bacteria (ARB) in the sediment of Sundarban estuary in India. Sci Total Environ. 647: 1626-1639. doi: 10.1016/j.scitotenv.2018.08.038

Mallick, I., Bhattacharyya, C., Mukherji, S., Dey, D., Sarkar, S.C., Mukhopadhyay, U.K., Ghosh, A*. (2018) Effective rhizoinoculation and biofilm formation by arsenic immobilizing halophilic plant growth promoting bacteria (PGPB) isolated from mangrove rhizosphere: A step towards arsenic rhizoremediation. Sci Total Environ. 610-611:1239-1250. (doi: 10.1016/j.scitotenv.2017.07.234)

Bhattacharyya, C., Bakshi, U., Mallick, I., Mukherji, S., Bera, B., and Ghosh, A*. (2017) Genome-guided insights into the plant growth promotion capabilities of the physiologically versatile Bacillus aryabhattai strain AB211. Frontiers in Microbiology 8:411 (doi: 10.3389/fmicb.2017.00411)

Bhattacharyya, A., Majumder, N.S., Basak, P., Mukherji, S., Roy, D., Nag, S., Haldar, A., Chattopadhyay, D., Mitra, S., Bhattacharyya, M.*, Ghosh, A.* (2015) Diversity and Distribution of Archaea in the Mangrove Sediment of Sundarbans. Archaea 968582. 

Basak, P., Majumder, N.S., Nag, S., Bhattacharyya, A., Roy, D., Chakraborty, A., SenGupta, S., Roy, A., Mukherjee, A., Pattanayak, R., Ghosh, A.*, Chattopadhyay, D.*, Bhattacharyya, M.* (2015) Spatiotemporal Analysis of Bacterial Diversity in Sediments of Sundarbans Using Parallel 16S rRNA Gene Tag Sequencing.  Microb Ecol 69: 500-511. 


Chakraborty, A., Bera, A., Mukherjee, A., Basak, P., Khan, I., Mondal, A., Roy, A., Bhattacharyya, A., SenGupta, S., Roy, D., Nag, S., Ghosh, A.*, Chattopadhyay, D.*, Bhattacharyya, M.* (2015) Changing bacterial profile of Sundarbans, the world heritage mangrove: Impact of anthropogenic interventions. World J Microb Biotechnol 31: 593-610. 

C) Collaborative research work:

Jain, S, Bhowmick, A, Jeong, B, Bae, T, Ghosh, A* (2022) Unravelling the physiological roles of mazEF Toxin-Antitoxin system on clinical MRSA strain by CRISPR RNA- guided cytidine deaminase. Journal of Biomedical Science 29:28. https://doi.org/10.1186/s12929-022-00810-5

Kaur, P, Ghosh, S, Bhowmick, A, Gadhave, K, Datta, S, Ghosh, A, Garg, N, Mahajan, R L, Basu, B, Choudhury, D. (2022) Bacterioboat, a novel tool to increase the half-life period of the orally administered drug. Science Advances 8, eabh1419. https://doi.org/10.1126/sciadv.abh1419

Bhattacharya, A, Ghosh, P, Singh, A, Ghosh, A, Bhowmick, A, Sinha, DK, Ghosh, A, Sen, P. (2021) Delineating the complex mechanistic interplay between NF-κβ driven mTOR depedent autophagy and monocyte to macrophage differentiation: A functional perspective. Cellular Signalling 110150 https://doi.org/10.1016/j.cellsig.2021.110150

Bhattacherjee, P, Roy, M, Naskar, A, Tsai, HC, Ghosh, A, Patra, N, John RP. (2021) A trinuclear copper (II) complex of naproxen‐appended salicylhydrazide: Synthesis, crystal structure, DNA binding and molecular docking study. Applied Organometallic Chemistry e6459 https://doi.org/10.1002/aoc.6459

Mukherjee D, Gupta S, Ghosh A, Ghosh A. (2020) Ustilago maydis secreted T2 ribonucleases, Nuc1 and Nuc2 scavenge extracellular RNA. Cellular Microbiology 22(12):e13256 

Manpoong, C, De Mandal, S, Bangaruswamy, D,K, Perumal, R,C, Benny, J, Beena, P,S, Ghosh, A, Senthil Kumar, N, Tripathi, S, K. (2020) Linking rhizosphere soil biochemical and microbial community characteristics across different land use systems in mountainous region in Northeast India. Meta Gene 23: 100625.

Chakraborty, P, Sarker, R, K, Roy, R, Ghosh, A, Maiti, D, Tribedi, P. (2019) Bioaugmentation of soil with Enterobacter cloacae AKS7 enhances soil nitrogen content and boosts soil microbial functional-diversity. 3 Biotech 9 (7): 253.

Roy, D, Pramanik, A, Banerjee, S, Ghosh, A, Chattopadhyay, D, Bhattacharyya, M. (2018) Spatio-temporal variability and source identification for metal contamination in the river sediment of Indian Sundarbans, a world heritage site. Environmental Science and Pollution Research 25(31):31326-31345.

Mahato, M., Mukherji, S., Van Hecke, K., Harms, K., Ghosh, A., Nayek, H.P. (2017) Mononuclear homoleptic organotin(IV) dithiocarbamates: Syntheses, structures and antimicrobial activities. Journal of Organometallic Chemistry, 853:27-34. (https://doi.org/10.1016/j.jorganchem.2017.10.027)

Vinayak, R., Dey, D., Ghosh, D., Chattopadhyay, D., Ghosh, A., Nayek, H.P. (2017) Schiff Base Supported Mononuclear Organotin(IV) Complexes: Syntheses, Structures and Fluorescence Cell Imaging. Applied Organometallic Chemistry  (doi: 10.1002/aoc.4122).

Basak, P., Pramanik, A., Sengupta, S., Nag, S., Bhattacharyya, A., Roy, D., Pattanayak, R., Ghosh, A., Chattopadhyay, D., and Bhattacharyya, M. (2016) Bacterial diversity assessment of pristine mangrove microbial community from Dhulibhashani, Sundarbans using 16S rRNA gene tag sequencing. Genomics Data 7:76-78.

Saha, S., Jana, S., Gupta, S., Ghosh, A*., and Nayek, H.P*. (2016) Syntheses, structures and biological activities of square  planar Ni(II), Cu(II) complexes. Polyhedron 107: 183-189.

Bera, A., Ghosh, A., Mukhopadhyay, A., Chattopadhyay, D., and Chakrabarti, K. (2015) Improvement of degummed ramie fiber properties upon treatment with cellulase secreting immobilized A. larrymoorei A1. Bioproc Biosyst Eng 38: 341-351.


Mahato, M., Dey, D., Pal, S., Saha, S., Ghosh, A., Harms, K., and Nayek, H.P. (2015) Syntheses, structures, optical properties and biological activities of bimetallic complexes. RSC Advances 4: 64725-64730.


Sengupta, S., Pramanik, A., Ghosh, A., and Bhattacharyya, M. (2015) Antimicrobial activities of actinomycetes isolated from unexplored regions of Sundarbans mangrove ecosystem. BMC Microbiol 15: 170.


Publication before joining Bose Institute:


Chaudhury, P., Neiner, T., D'Imprima, E., Banerjee, A., Reindl, S., Ghosh, A., Arvai, A.S., Mills, D.J., van der Does, C., Tainer, J.A., Vonck, J., and Albers S.V. (2016) The nucleotide-dependent interaction of FlaH and FlaI is essential for assembly and function of the archaellum motor. Mol Microbiol 99: 674-685.

Henche, A.L., van Wolferen, M., Ghosh, A.*, and Albers, S.V.* (2014) Dissection of key determinants of cleavage activity in  signal peptidase III (SPaseIII) PibD. Extremophiles 18: 905-913. (*Corresponding authors)

Wagner, M., Wagner, A., Ma, X., Kort, J.C., Ghosh, A., Rauch, B., Siebers, B., and Albers, S.V. (2014) Investigation of the malE promoter and MalR, a positive regulator of the maltose regulon, for an improved expression system in Sulfolobus acidocaldarius.  Appl Env Microbiol 80: 1072-1081.

Reindl, S. *, Ghosh, A.*, Williams, G.J. *, Lassak, K., Neiner, T., Henche, A.L., Albers, S.V., and Tainer, J.A. (2013) Insights into FlaI functions in archaeal motor assembly and motility from structures, conformations, and genetics. Molecular Cell 49: 1069-1082. (* contributed equally)

Banerjee, A., Ghosh, A., Mills, D.J., Kahnt, J., Vonck, J., and Albers, S.V. (2012) FlaX, A Unique Component of the Crenarchaeal Archaellum, Forms Oligomeric Ring-shaped Structures and Interacts with the Motor ATPase FlaI. J Biol Chem 287: 43322-43330.

Henche, A.L., Ghosh, A., Yu, X., Jeske, T., Egelman, E., and Albers, S.V. (2012)  Structure and function of the adhesive type IV pilus of Sulfolobus acidocaldarius. Environ Microbiol 14: 3188-3202.

Henche, A.L., Koerdt, A., Ghosh, A., and Albers, S.V. (2012) Influence of cell surface structures on crenarchaeal biofilm formation using a thermostable green fluorescent protein. Environ Microbiol 14: 779-793.

Lassak, K., Neiner, T., Ghosh, A., Klingl, A., Wirth, R., and Albers, S.V. (2012) Molecular analysis of the crenarchaeal flagellum. Mol Microbiol 83: 110-124.

Koerdt, A., Jachlewski, S., Ghosh, A., Wingender, J., Siebers, B., and Albers, S.V. (2012) Complementation of Sulfolobus solfataricus PBL2025 with an alpha-mannosidase: effects on surface attachment and biofilm formation. Extremophiles 16: 115-125.

Ray, R., Ghosh, A., Bera, A., Dutta, N., Chattopadhyay, D.J., and Chakrabarti, K. (2011)  Analysis of differentially expressed transcripts in jute upon fungal infection and beta-amino butyric acid treatment. Physiol Mol Plant Physiol 76: 59-66.

Ghosh, A., Hartung, S., van der Does, C., Tainer, J.A., and Albers, S.V. (2011) Archaeal flagellar ATPase motor shows ATP-dependent hexameric assembly and activity stimulation by specific lipid binding. Biochem J 437: 43-52.

Basu, S., Roy, A., Ghosh, A., Bera, A., Chattopadhyay, D., and Chakrabarti, K. (2011) Arg(235) is an essential catalytic residue of Bacillus pumilus DKS1 pectate lyase to degum ramie fibre. Biodegradation 22: 153-161.

Ghosh, A., Dey, N., Bera, A., Tiwari, A., Sathyaniranjan, K., Chakrabarti, K., and Chattopadhyay, D. (2010) Culture independent molecular analysis of bacterial communities in the mangrove sediment of Sundarban, India. Saline Systems 6:1.

Ghosh, A., Chakrabarti, K., and Chattopadhyay, D. (2009) Cloning of feather-degrading minor extracellular protease from Bacillus cereus DCUW: dissection of the structural domains. Microbiology 155: 2049-2057.

Barua, S., Tripathi, S., Ghosh, A., Chakraborty, A., Ghosh, S., and Chakrabarti, K. (2008) Studies on Non-symbiotic Diazotropic Bacterial Population of the saline Soils of Sundarbans. J Pure Appl Microbiol 2: 355-364.

Ghosh, A., Chakrabarti, K., and Chattopadhyay, D. (2008) Degradation of raw feather by a novel high molecular weight extracellular protease from newly isolated Bacillus cereus DCUW. J Ind Microbiol Biotechnol 35: 825-834.

Basu, S., Ghosh, A., Bera, A., Saha, M.N., Chattopadhyay, D., and Chakrabarti, K. (2008) Thermodynamic characterization of a highly thermoactive extracellular pectate lyase from a new isolate Bacillus pumilus DKS1. Bioresource Technology 99: 8088-8094.

Sinan, M., Panda, M., Ghosh, A., Dhara, K., Fanwick, P.E., Chattopadhyay, D.J., and Goswami, S. (2008) Mild synthesis of a family of planar triazinium cations via proton-assisted cyclization of pyridyl containing azo compounds and studies on DNA intercalation. J American Chem Soc 130: 5185-5193.

Saha, B., Singh, A.K., Ghosh, A., and Bal, M. (2008) Identification and characterization of a vancomycin-resistant Staphylococcus aureus isolated from Kolkata (South Asia). J Med Microbiol 57: 72-79.

Ghosh, A., Basu, S., Datta, H., and Chattopadhyay, D. (2007) Evaluation of polymerase chain reaction-based ribosomal DNA Sequencing technique for the diagnosis of mycotic keratitis. Am J Ophthalmol 144: 396-403.

Ghosh, A., Maity, B., Chakrabarti, K., and Chattopadhyay, D. (2007) Bacterial diversity of east calcutta wet land area: Possible identification of potential bacterial population for different biotechnological uses. Microb Ecol 54: 452-459.

Review articles:

Roy, M, Bhakta, K, Ghosh, A*. (2022) Minimal Yet Powerful: The Role of Archaeal Small Heat Shock Proteins in Maintaining Protein Homeostasis. Front. Mol. Biosci., 9:832160 https://doi.org/10.3389/fmolb.2022.832160

Bhattacharyya, S., Sharma, P., Mitra, S., Mallick, I., Ghosh, A. (2021) Arsenic uptake and bioaccumulation in plants: A review on remediation and socio-economic perspective in Southeast Asia. Env. Nanotech Montoring Management 15:100430.

Haldar, S., & Ghosh, A*. (2020) Microbial and plant-assisted heavy metal remediation in aquatic ecosystems: a comprehensive review. 3 Biotech 10:1-13.

Gupta, S., Roy, M., and Ghosh, A*. (2017) The Archaeal Signal Recognition Particle: Present Understanding and Future Perspective. Current microbiology 74:284-297.

Mahanty, T., Bhattacharjee, S., Goswami, M., Bhattacharyya, P., Das, B., Ghosh, A., and Tribedi, P. (2016) Biofertilizers: a potential approach for sustainable agriculture development. Environ Sci Pol Res Int 24: 3315–3335. (doi: 10.1007/s11356-016-8104-0)

Lassak, K., Ghosh, A., and Albers, S.V. (2012) Diversity, assembly and regulation of archaeal type IV pili-like and non-type-IV pili-like surface structures. Res Microbiol 163: 630-644.

Pohlschroder, M., Ghosh, A., Tripepi, M., and Albers, S.V. (2011) Archaeal type IV pilus-like structures-evolutionarily conserved prokaryotic surface organelles. Curr Opin Microbiol 14: 357-363.

Ghosh, A., and Albers, S.V. (2011) Assembly and function of the archaeal flagellum. Biochem Soc Trans 39: 64-69.

 

Book Chapters:

Haldar, S, Mondal, S, Kumari, A, Ghosh, A, Chattopadhyay, D, Ghosh, A*. (2021) Rhizosphere microbiome engineering. In Ashok Pandey (eds.), Designer Microbial Cell Factories: Metabolic Engineering and Applications. (In press)

 

Haldar, S, Kumari, A, Ghosh, A, Ghosh, A*. (2020) Influence of Biotic and Abiotic Stresses on Quinoa Cultivation: Insights into Microbe Assisted Stress Tolerance. In Ajit K. Varma (eds.), Biology and Biotechnology of Quinoa. January 2022


Bhattacharyya, C, Roy, R, Tribedi, P, Ghosh, A, Ghosh, A*. (2020) Biofertilizers as substitute to commercial agrochemicals. In M.N.V. Prasad (eds.), Agrochemicals Detection, Treatment and Remediation, Pesticides and Chemical Fertilizers, January 2020, 263-290 (ISBN   978-0-081-03017-2). https://www.elsevier.com/books/agrochemicals-detection-treatment-and-remediation/prasad/978-0-08-103017-2


Mukherji, S, Haldar, S, Ghosh, A*. (2019) Investigation of the Structural and Functional Microbial Diversity in Indian Mangroves. B. Giri, A. Varma (eds.), Microorganisms in Saline Environments: Strategies and Functions, Soil Biology, July 2019, 56: 93-130 (ISBN 978-3-030-18974-7). https://link.springer.com/chapter/10.1007/978-3-030-18975-4_5


Mallick, I, Ghosh, A, Ghosh, A*. (2019) Microbe-Mediated Removal of Heavy Metals for Sustainable Agricultural Practices. B. Giri et al. (eds.), Biofertilizers for Sustainable Agriculture and Environment, Soil Biology, August 2019, 55: 521-544 (ISBN 978-3-030-18932-7). 


Dutta, P., Mallick, I., Ghosh, A., and Basu, M. (2018) Study of Some Predominant Arsenic Resistance Bacteria from Soil Samples of Industrial Zones of West Bengal, India. Utilization  and Management of Bioresources, by Springer Publisher Inc., January, pp: 195-208 (ISBN:978-981-10-5349-8).

Ghosh, A and Chattopadhyay, D.J. (2011) Feather-degrading enzymes and their prospective applications. Advances in Bioprocesses in Food Industries, Vol IV by Soccol et. al. published by AsiaTech Publisher Inc. (ISBN: 9788187680284)

 

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Recognition:

  • Recipient of Carl Storm International Diversity Fellowship for attending the Gordon Research Conferences: Structural, Functional, and Evolutionary Genomics at Wellcome Trust Conference Centre, Hinxton, Cambridge, United Kingdom, 2007
  • Recipient of FEMS Congress Grant for Young Scientists from Federation of European Microbiological Society (FEMS) at the 4th FEMS Congress of European Microbiologists at PALEXPO, Geneva, Switzerland, 2011
  • Recipient of Max Planck Postdoctoral Fellowship , 2008-2012
  • Selected as UGC-Assistant Professor through UGC-Faculty Recharge Program (UGC-FRP) by University Grant Commission (UGC), 2012
  • Selected as the Ramanujan Fellow by Department of Science and Technology (DST), India, 2013
  • Recipient of DST-Fast Track Scheme for Young Scientists, 2014
  • Recipient of EMBO travel grant to attend EMBO workshop on “Molecular biology of archaea: From mechanisms to ecology” at the University of Vienna, Austria, 2018
  • Recipient of IGSTC (Indo German Science and Technology Centre) grant to attend Indo-German bilateral workshop on “Agricultural Management Practice Effects on Soil- And Plant-associated bacterial communities and their resistome” at Leibniz Institute of Agricultural Engineering and Bio-economy e.V. (ATB), Potsdam, Germany, 2022
  • Recipient of Vigyan Sera Protiva award in the VIGYAN UTSOV organized by Central Calcutta Science & Culture Organisation for Youth (CCSCOY) in co-operation with the Department Of Science & Technology And Biotechnology, Govt of West Bengal , 2022

Teaching:

Bose Institute (MSc--‐PhD): Biophysical techniques (Chromatography), Prokaryotic Molecular Biology; Department of Genetics, Calcutta University (M Sc): Prokaryotic genetics; Bose Institute, Kolkata (PhD coursework): Biophysical techniques (Chromatography).

Students:

Image Name Designation Department Campus Contact number Email
profile image Agnita Acharya Junior Research Fellow Biochemistry Unified acharyatheagnita@gmail.com
profile image Arghya Bhowmick Senior Research Fellow Biochemistry Centenary arghyabhowmick@jcbose.ac.in
profile image Jagriti Das Junior Research Fellow Biochemistry Unified jagridas85@gmail.com
profile image Shirsha Samanta Junior Research Fellow Biochemistry Unified samantashirsha07@gmail.com

Postdoctoral Fellows / RA :

Image Name Designation Department Campus Contact number Email
profile image Triparna Mukherjee Research Associate Biochemistry Centenary 25693238

Former:

1. Dr. Ivy Mallick (Commissioning Editor, Springer Nature Group, Netherlands)

2. Dr. Somi Patranabis (Assistant Professor, Amity University, Kolkata, India)

3. Dr. Dhritiman Dey (Postdoc at University of Toledo, USA)

4. Dr. Anish Bhattacharyya (Postdoc at the University of Manchester, United Kingdom)

5. Dr. Mousam Roy (Postdoc at Weizmann Institute of Science, Israel)

6. Dr. Sayandeep Gupta (Postdoc at University of Oregon, USA)

7. Dr. Shayantan Mukherji (Research Scientist, Reliance Industries Ltd., Mumbai, India)

8. Dr. Chandrima Bhattacharyya (Postdoc)

9. Dr. Triparna Mukherjee (Assistant Professor, Brainware University, Kolkata, India)

Group News:

Openings: 

PhD: Positions are presently available for students willing to pursue PhD in area of microbial genomics/ microbial stress response. Candidates who have secured fellowships through NET or any other equivalent examination can send their CV along with a cover letter to aghosh78@gmail.com

RA/Postdoc: Candidates willing to carry out postdoctoral research in the area of the microbial stress response with experience on haloarchaea may go through our research profile and can contact directly by email to Dr. Abhrajyoti Ghosh at aghosh78@gmail.com. We encourage candidates to apply for DBT RA, ICMR RA, SERB-NPDF etc.

We are presently looking for postdoctoral candidates having experience in genomic/ metagenomic and transcriptomic analysis. Interested candidates may contact directly to Dr. Abhrajyoti Ghosh at aghosh78@gmail.com.

News and updates: 

03/01/2022: Congratulations to CSIR adhoc SRF Mr. Arghya Bhowmick on being successfully promoted to the final year of his Ph.D. by CSIR, Govt. of India

19/01/2022: Ms. Jagriti Das has joined our lab as a DBT-JRF. She will be carrying out her research in the biochemistry section of our group. We welcome her to our lab.

19/01/2022: Ms. Agnita Acharya has joined our lab as an INSPIRE-JRF. She will be carrying out her research in the microbial ecology section of our group. We welcome her to our lab.

21/02/2022: Ms. Chandrima Bhattacharyya successfully defended her thesis titled “Exploring the Microbioal Diversity in Tea Rhizosphere and an Assessment of Resident Plant Growth Promoting Rhizobacteria.” We wish her all the best in her future endeavours.

21/02/2022: Mr. Shayantan Mukherji successfully defended his thesis titled “Microbiology of Sundarban Mangrove Ecosystem: Insights into Diversity, Distribution and Function of Resident Microbial Communities.”  We wish him all the best in his future endeavours.

08/04/2022: Mr. Sayandeep Gupta presented his work, titled as “Targeting Complex Formation in Thermoacidophilic Archaea is Facilitated by RNA”, in the Annual Meeting of Society of Biological Chemists, Kolkata Chapter. We are glad to have his research recognized.

08/04/2022: Mr. Shayantan Mukherji presented a poster titled “Exploring the Unknown: Studies into the Microbiology of Sundarban Mangrove Ecosystem”, in the Annual Meeting of Society of Biological Chemists, Kolkata Chapter. We are glad to have his research recognized.

18/05/2022: Dr. Dhruba Bhattacharya has joined the lab as SERB-NPDF. We hope his addition to our family will bring new insights into the collective effort.

20/06/2022-22/06/2022: Dr. Abhrajyoti Ghosh participated and delivered an invited lecture entitled “Spatial dynamics and ecological dissemination mechanism of antibiotic resistome in the mangrove sediment of Sundarban, India” in the Indo German Science and Technology Centre sponsored Indo-German bilateral workshop on “Agricultural Management Practice Effects on Soil and Plant associated bacterial communities and their resistome” at Leibniz Institute of Agricultural Engineering and Bioeconomy e.V. (ATB), Postdam, Germany.

01/08/2022-04/08/2022: Mr. Arghya Bhowmick presented a poster titled “The Role of Type-II Toxin Antitoxin System in Cross Stress Adaptation in Sulfolobus acidocaldarius” at the EMBO workshop 2022 on Molcular Biology of Archaea at Goethe University in Frankfurt, Germany. He received travel support from DBT-CTEP grant, CSIR and EMBO. We are glad to have his research recognized at an international platform.

03/08/2022: Congratulations to Institute SRF Mr. Koustav Bhakta on being successfully promoted to the final year of his Ph.D. by Bose Institute.

25/08/2022: Dr. Triparna Mukherjee got recruited as an Assistant Professor in the Department of Biotechnology, Brainware University, Kolkata, West Bengal. We extend our heartiest congratulation to her and wish her all the best in her future endeavours.

01/09/2022: It's a bitter-sweet moment for the lab as Dr. Sayandeep Gupta bid us adieu. He got selected as a postdoctoral researcher in the Department of Bioengineering, University of Oregon Phil and Penny Knight Campus for Accelerating Scientific Impact. Though we will miss his amiable presence among us, we surely wish him the best for his career.

09/09/2022: Mr. Sayandeep Gupta successfully defended his thesis titled “Understanding the Mechanism of RNA-Protein Interaction Involved in the Protein Translocation in Archaea.”  We wish him all the best in his future endeavours.

20/09/2022: Congratulations to Ms. Sangita Mondal on being successfully promoted to UGC-adhoc SRF by UGC, government of India.

20/10/2022: Dr. Shayantan Mukherji got recruited as a Research Scientist in Reliance Industries Limited. We extend our heartiest congratulation to him for being the first one from our lab to pave the way to industrial research.

23/10/2022-28/10/2022: Mr. Koustav Bhakta presented a poster titled “Protection and Perfection: Insights into the Protein Folding Mechanism of Heat Shock Proteins in Archaea” at the Gordon Research Conference (Protein Folding Dynamics), Folding and Misfolding: Effects of Evolution and Environment 2022 held at Four Points Sheraton / Holiday Inn Express in California, United States. He received travel support from DBT-CTEP grant and SERB-ITS. We are glad to have his research recognized at an international platform.

04/11/2022-06/11/2022: Dr. Dhruba Bhattacharya and Mr. Arghya Bhowmich participated in Biological Engineering Society Conference 2022 (BESCON 2022) organized by IIT-Kharagpur and Bose Institute.

28/11/2022: Mr. Arghya Bhowmick presented a poster titled “The Role of Type-II Toxin Antitoxin System in Cross Stress Adaptation in Sulfolobus acidocaldarius” at the student symposium held on the occasion of 106th foundation day of Bose Institute.

28/11/2022: Ms. Jagriti Das presented a poster titled “Understanding the Regulation of Type-II Toxin Antitoxin System in Sulfolobus acidocaldarius” at the student symposium held on the occasion of 106th foundation day of Bose Institute.

28/11/2022: Ms. Agnita Acharya presented a poster titled “Understanding osmoadaptation in the Light of Salinity Fluctuations in Sundarban Mangroves” at the student symposium held on the occasion of 106th foundation day of Bose Institute.

28/11/2022: Ms. Sangita Mondal presented a poster titled “Exploring the Plant Growth Promoting Potential of Rhizobacteria Isolated from Tea Rhizospheric Soil of Darjeeling” at the student symposium held on the occasion of 106th foundation day of Bose Institute.

28/11/2022: Mr. Koustav Bhakta presented his work titled “Protection and Perfection: Insights into the Protein Folding Mechanism of Heat Shock Proteins in Archaea” at the student symposium held on the occasion of 106th foundation day of Bose Institute. He received an award for the best oral presentation from Prof. Asutosh Sharma (DST secretary). We congratulate him for his achievement.