Abhrajyoti Ghosh
Associate Professor
Abhrajyoti Ghosh
Associate Professor, Biological Sciences
PhD: Department of Biochemistry, University of Calcutta, 2008
Previous appointments:
1. Max Planck Postdoctoral Fellow at Max Planck Institute for Terrestrial Microbiology, Marburg, Germany (2008-2012).
2. Research Associate at Department of Biochemistry, University of Calcutta (2012-2013).
3. DST-Ramanujan Fellow at Department of Biochemistry, Bose Institute (2014-2018).
4. Assistant professor, Department of Biochemistry, Bose Institute (2016-2020).
Research interests:
My laboratory is involved in understanding
microbial stress response and adaptation. We use a variety of techniques starting with biochemistry, microbiology,
and genomics, for identification & characterization of the molecular
players important in the survival of microorganisms in the natural environment.
Contact:
| Address: |
Biological Sciences Unified Academic Campus Bose Institute EN-80, Sector V Bidhan Nagar Kolkata - 700 091, India |
| E-Mail: | abhrajyoti.ghosh[at]jcbose.ac.in |
| Phone: | +91-33-25693284 |
Research:
Archaeal stress response:
The study of archaea, the third domain of life can provide interesting insights into the evolutionary
history of different cellular pieces of machinery and mechanisms across all life forms.
One such mechanism of our concern is that of protein translocation across biological
membranes in archaea. Our present focus is on the structural and functional
analyses of molecules that are central to the archaeal secretion process under
different limiting conditions. Since archaea can sustain such extreme limiting
conditions, withstanding different kinds of stresses, we also aim to get a
thorough idea about the effect of different types of stressors on archaeal
cells at the transcriptomic and proteomic levels. We want to study the fate of
stress-related proteins under conditions of stress, which includes
identification, characterization, and analysis of the mode of regulation of
stress-related proteins and their targets. Therefore, the current research in
our lab is concerned with understanding the effect of heat stress on archaea in
regard to different molecular chaperones. In addition, our recent venture is to
study the role of toxin-antitoxin systems in stress adaptation in archaea.
Stress adaptation of environmental microbes:
A changing environment creates conditions that can be
stressful for microorganisms. To cope with environmental stress, microbes have
a variety of evolutionary adaptations and physiological acclimatization
mechanisms. Such adaption and acclimatization strategies allow them to survive
and remain metabolically active in the face of environmental stress. However,
not all microorganisms are equipped with the necessary arsenals to adapt to the
changing environment, and therefore a shift in microbial community composition
is often documented under stress conditions. It is believed to be mainly due to
a change in ecosystem-level carbon, energy, and nutrient flows that drive
alteration in microbial dynamics.
In contrast to
conventional strategies of understanding specific organismal responses to
environmental stress, our approach aims at developing a more reliable
connection between microbial and ecosystem ecology. In our laboratory, we study the diversity,
distribution, and function of microorganisms (archaeal and bacteria) in the natural
environment. We study microbial structure and function in two unique
ecosystems, i.e., the Sundarban mangrove ecosystem and the tea plantation ecosystem
of Darjeeling. We adopt genomic and proteomic approaches to find out novel
metabolic pathways involved in either heavy metal resistance, antimicrobial
resistance, biocatalysis, and novel antimicrobial biosynthesis, etc., in the
resident microorganisms. Moreover, we extend our interest in a study of the host
(plant)-associated microbiome in these environments. Plants are intimately associated with vast numbers of microorganisms in the rhizosphere.
The rhizosphere microbiome is not static, and the microbial community structure
in the rhizosphere micro-niche can change in response to stresses and environmental
stimuli. Recent studies support that the changes in the rhizosphere microbiome
are not merely passive responses of plants but rather, as a consequence of
millions of years coevolution, plants likely actively seek cooperation with
microbes to fight stresses. We study the rhizosphere microbiome of mangrove
plants and tea plants with particular emphasis on plant-growth-promoting
rhizobacteria (PGPR).
Publications:
Publication from Bose
Institute:
A) Archaeal
stress response:
Bhowmick, A, Bhakta, K, Roy, M, Gupta, S, Das, J, Samanta, S, Patranabis, S, Ghosh, A.* (2023) Heat shock response in Sulfolobus acidocaldarius and first implications for cross-stress adaptation. Research in Microbiology, 104106. https://doi.org/10.1016/j.resmic.2023.104106 (*Corresponding author)
Roy, M, Bhakta, K,
Bhowmick, A, Gupta, S, Ghosh, A, Ghosh, A*. (2022) Archaeal
Hsp14 drives substrate shuttling between small heat shock proteins and
thermosome: insights into a novel substrate transfer pathway. FEBS
Journal 289(4): 1080-1104 https://doi.org/10.1111/febs.16226
Gupta, S, Sinha, S,
Bhakta, K, Bhowmick, A, Ghosh, A*. (2022) N-terminal helices and A
domain of archaeal FtsY facilitate SRP54 binding and the association with cell
membrane. bioRxiv 2022.04.13.488184; doi: https://doi.org/10.1101/2022.04.13.488184
Gupta, S, Roy, M, Dey,
D, Bhakta, K, Bhowmick, A. Chattopahyay, D, Ghosh, A*. (2021) Archaeal
SRP RNA and SRP19 facilitate the assembly of SRP54-FtsY targeting
complex. Biochemical and Biophysical Research Communications 566:53-58.
Roy, M, Gupta, S,
Patranabis, S, Ghosh, A*. (2018) The oligomeric
plasticity of Hsp20 of Sulfolobus acidocaldarius protects environment-induced
protein aggregation and membrane destabilization. BBA-Biomembranes 1860(12):
2549-2565.
B) Stress adaptation of environmental
microbes:
Mukherji, S, Imchen, M, Mondal, S, Bhattacharyya, A, Siddhartha, B, Kumavath, R, Ghosh, A*. (2022) Anthropogenic impact accelerates antibiotic resistome diversity in the mangrove sediment of Indian Sundarban. Chemosphere 309: 136806
Mukherji, S, Bakshi, U, Ghosh, A*. (2022) Draft genome sequences of hydrocarbon degrading Haloferax sp. AB510, Haladaptatus sp. AB618 and Haladaptatus sp. AB643 isolated from the estuarine sediments of Sundarban mangrove forests, India. 3 Biotech 12: 204. https://doi.org/10.1007/s13205-022-03273-5
Bhattacharyya,
C, Imchen, M, Mukherjee, T, Haldar, S, Mondal, S,
Mukherji, S, Haldar, A, Kumavath, R, Ghosh, A*. (2022) Rhizosphere
impact bacterial community structure in the tea (Camellia sinensis (L.) O.
Kuntze.) estates of Darjeeling, India. Environmental Microbiology
24(6): 2716-2731 https://doi.org/10.1111/1462-2920.15874
Bhattacharya C, Banerjee S, Acharya U, Mitra
A, Mallick I, Halder A, Haldar S, Ghosh A*, Ghosh A*. (2020) Evaluation
of plant growth promotion and induction of antioxidative defense mechanism by
rhizobacteria isolated from tea rhizosphere of Darjeeling, India. Scientific
Reports 10(1): 15536 (*Corresponding
authors)
Mukherji, S, Ghosh, A,
Bhattacharyya, C, Mallick, I, Anish Bhattacharyya, A, Mitra, S, Ghosh,
A*. (2020) Molecular and culture-based surveys of
metabolically active hydrocarbon-degrading archaeal communities in Sundarban
mangrove sediments. Ecotox Environ Safety 195:110481.
Bhattacharyya, A,
Haldar, A, Bhattacharyya, M, Ghosh, A*. (2019) Anthropogenic
influence shapes the distribution of antibiotic resistant bacteria (ARB) in the
sediment of Sundarban estuary in India. Sci Total Environ. 647:
1626-1639. doi: 10.1016/j.scitotenv.2018.08.038
Mallick, I.,
Bhattacharyya, C., Mukherji, S., Dey, D., Sarkar, S.C., Mukhopadhyay,
U.K., Ghosh, A*. (2018) Effective rhizoinoculation
and biofilm formation by arsenic immobilizing halophilic plant growth promoting
bacteria (PGPB) isolated from mangrove rhizosphere: A step towards arsenic
rhizoremediation. Sci Total Environ. 610-611:1239-1250.
(doi: 10.1016/j.scitotenv.2017.07.234)
Bhattacharyya, C.,
Bakshi, U., Mallick, I., Mukherji, S., Bera, B., and Ghosh, A*. (2017) Genome-guided
insights into the plant growth promotion capabilities of the physiologically
versatile Bacillus aryabhattai strain AB211. Frontiers in
Microbiology 8:411 (doi: 10.3389/fmicb.2017.00411)
Bhattacharyya, A.,
Majumder, N.S., Basak, P., Mukherji, S., Roy, D., Nag, S., Haldar, A.,
Chattopadhyay, D., Mitra, S., Bhattacharyya, M.*, Ghosh, A.* (2015) Diversity
and Distribution of Archaea in the Mangrove Sediment of Sundarbans. Archaea 968582.
Basak, P., Majumder,
N.S., Nag, S., Bhattacharyya, A., Roy, D., Chakraborty, A., SenGupta, S., Roy,
A., Mukherjee, A., Pattanayak, R., Ghosh, A.*, Chattopadhyay, D.*,
Bhattacharyya, M.* (2015) Spatiotemporal Analysis of Bacterial
Diversity in Sediments of Sundarbans Using Parallel 16S rRNA Gene Tag
Sequencing. Microb Ecol 69: 500-511.
Chakraborty, A., Bera, A., Mukherjee, A., Basak, P., Khan, I., Mondal, A., Roy,
A., Bhattacharyya, A., SenGupta, S., Roy, D., Nag, S., Ghosh, A.*,
Chattopadhyay, D.*, Bhattacharyya, M.* (2015) Changing
bacterial profile of Sundarbans, the world heritage mangrove: Impact of
anthropogenic interventions. World J Microb Biotechnol 31:
593-610.
C) Collaborative research work:
Dey, D, Dasgupta, A, Ghosh, D, Bhattacharjee, O, Ghosh, A, Honda, A, Chattopadhyay, D. (2023) Host proteins Alpha-2-Macroglobulin and LRP1 associate with Chandipura virus. Biochimie 28:218:105-117. https://doi.org/10.1016/j.biochi.2023.07.019
Mitra, A, Bhakta, K, Kar, A, Roy, A, Mohid, SA, Ghosh, A*, Ghosh, A*. (2023) Insight into the biochemical and cell biological function of an intrinsically unstructured heat shock protein, Hsp12 of Ustilago maydis. Molecular Plant Pathology 24 (9), 1063-1077. https://doi.org/10.1111/mpp.13350
Modi B, Bahadur S, Bhowmik P, Chakraborti S, Dirisala A, et al., (2023) Curcumin and Colistin are Synergistic in Inhibiting the Growth and Biofilm Formation of Pseudomonas aeruginosa Isolated from Environmental Sample. Infect Dis Diag Treat 7: 218. https://doi.org/10.29011/2577-1515.100218
Mukherjee, S, Bhakta, K, Ghosh, A, Ghosh, A. (2022) Ger1 is a secreted aspartic acid protease essential for spore germination in Ustilago maydis. Yeast https://doi.org/10.1002/yea.3835
Jain, S, Bhowmick, A, Jeong, B, Bae, T, Ghosh,
A* (2022) Unravelling the physiological roles of mazEF Toxin-Antitoxin
system on clinical MRSA strain by CRISPR RNA- guided cytidine deaminase. Journal
of Biomedical Science 29:28. https://doi.org/10.1186/s12929-022-00810-5
Kaur, P, Ghosh, S, Bhowmick, A, Gadhave, K,
Datta, S, Ghosh, A, Garg, N, Mahajan, R L, Basu, B, Choudhury, D. (2022)
Bacterioboat, a novel tool to increase the half-life period of the orally
administered drug. Science Advances 8, eabh1419. https://doi.org/10.1126/sciadv.abh1419
Bhattacharya, A, Ghosh, P, Singh, A, Ghosh, A,
Bhowmick, A, Sinha, DK, Ghosh, A, Sen, P. (2021) Delineating the complex mechanistic
interplay between NF-κβ driven mTOR depedent autophagy and monocyte to
macrophage differentiation: A functional perspective. Cellular Signalling 110150 https://doi.org/10.1016/j.cellsig.2021.110150
Bhattacherjee, P, Roy, M, Naskar, A, Tsai, HC, Ghosh,
A, Patra, N, John RP. (2021) A trinuclear copper (II) complex of naproxen‐appended salicylhydrazide:
Synthesis, crystal structure, DNA binding and molecular docking study. Applied Organometallic Chemistry e6459 https://doi.org/10.1002/aoc.6459
Mukherjee D, Gupta
S, Ghosh A, Ghosh A. (2020) Ustilago maydis secreted
T2 ribonucleases, Nuc1 and Nuc2 scavenge extracellular RNA. Cellular
Microbiology 22(12):e13256
Manpoong, C, De
Mandal, S, Bangaruswamy, D,K, Perumal, R,C, Benny, J, Beena, P,S, Ghosh,
A, Senthil Kumar, N, Tripathi, S, K. (2020) Linking
rhizosphere soil biochemical and microbial community characteristics across
different land use systems in mountainous region in Northeast India. Meta
Gene 23: 100625.
Chakraborty, P,
Sarker, R, K, Roy, R, Ghosh, A, Maiti, D, Tribedi, P. (2019) Bioaugmentation
of soil with Enterobacter cloacae AKS7 enhances soil nitrogen
content and boosts soil microbial functional-diversity. 3 Biotech 9
(7): 253.
Roy, D, Pramanik, A,
Banerjee, S, Ghosh, A, Chattopadhyay, D, Bhattacharyya, M. (2018)
Spatio-temporal variability and source identification for metal contamination
in the river sediment of Indian Sundarbans, a world heritage site. Environmental
Science and Pollution Research 25(31):31326-31345.
Mahato, M., Mukherji,
S., Van Hecke, K., Harms, K., Ghosh, A., Nayek, H.P. (2017) Mononuclear
homoleptic organotin(IV) dithiocarbamates: Syntheses, structures and
antimicrobial activities. Journal of Organometallic Chemistry,
853:27-34. (https://doi.org/10.1016/j.jorganchem.2017.10.027)
Vinayak, R., Dey, D.,
Ghosh, D., Chattopadhyay, D., Ghosh, A., Nayek, H.P. (2017) Schiff
Base Supported Mononuclear Organotin(IV) Complexes: Syntheses, Structures and
Fluorescence Cell Imaging. Applied Organometallic Chemistry (doi:
10.1002/aoc.4122).
Basak, P., Pramanik,
A., Sengupta, S., Nag, S., Bhattacharyya, A., Roy, D., Pattanayak, R., Ghosh,
A., Chattopadhyay, D., and Bhattacharyya, M. (2016) Bacterial
diversity assessment of pristine mangrove microbial community from Dhulibhashani,
Sundarbans using 16S rRNA gene tag sequencing. Genomics Data 7:76-78.
Saha, S., Jana, S.,
Gupta, S., Ghosh, A*., and Nayek, H.P*. (2016) Syntheses,
structures and biological activities of square planar Ni(II), Cu(II)
complexes. Polyhedron 107: 183-189.
Bera, A., Ghosh,
A., Mukhopadhyay, A., Chattopadhyay, D., and Chakrabarti, K. (2015) Improvement
of degummed ramie fiber properties upon treatment with cellulase secreting
immobilized A. larrymoorei A1. Bioproc Biosyst
Eng 38: 341-351.
Mahato, M., Dey, D., Pal, S., Saha, S., Ghosh, A., Harms, K., and
Nayek, H.P. (2015) Syntheses, structures, optical properties
and biological activities of bimetallic complexes. RSC Advances 4:
64725-64730.
Sengupta, S., Pramanik, A., Ghosh, A., and Bhattacharyya, M. (2015) Antimicrobial
activities of actinomycetes isolated from unexplored regions of Sundarbans
mangrove ecosystem. BMC Microbiol 15: 170.
Publication before joining Bose Institute:
Chaudhury, P., Neiner,
T., D'Imprima, E., Banerjee, A., Reindl, S., Ghosh, A., Arvai,
A.S., Mills, D.J., van der Does, C., Tainer, J.A., Vonck, J., and Albers
S.V. (2016) The nucleotide-dependent interaction of FlaH and FlaI is
essential for assembly and function of the archaellum motor. Mol
Microbiol 99: 674-685.
Henche, A.L., van
Wolferen, M., Ghosh, A.*, and Albers,
S.V.* (2014) Dissection of key determinants of cleavage activity
in signal peptidase III (SPaseIII) PibD. Extremophiles 18:
905-913. (*Corresponding authors)
Wagner, M., Wagner,
A., Ma, X., Kort, J.C., Ghosh, A., Rauch, B., Siebers, B., and
Albers, S.V. (2014) Investigation of the malE promoter and MalR, a
positive regulator of the maltose regulon, for an improved expression system
in Sulfolobus acidocaldarius. Appl Env Microbiol 80:
1072-1081.
Reindl, S. *, Ghosh,
A.*, Williams, G.J. *, Lassak, K., Neiner, T., Henche, A.L., Albers, S.V.,
and Tainer, J.A. (2013) Insights into FlaI functions in archaeal
motor assembly and motility from structures, conformations, and genetics. Molecular
Cell 49: 1069-1082. (* contributed equally)
Banerjee, A., Ghosh,
A., Mills, D.J., Kahnt, J., Vonck, J., and Albers,
S.V. (2012) FlaX, A Unique Component of the Crenarchaeal Archaellum,
Forms Oligomeric Ring-shaped Structures and Interacts with the Motor ATPase
FlaI. J Biol Chem 287: 43322-43330.
Henche, A.L., Ghosh,
A., Yu, X., Jeske, T., Egelman, E., and Albers,
S.V. (2012) Structure and function of the adhesive type IV
pilus of Sulfolobus acidocaldarius. Environ
Microbiol 14: 3188-3202.
Henche, A.L., Koerdt,
A., Ghosh, A., and Albers, S.V. (2012) Influence of cell
surface structures on crenarchaeal biofilm formation using a thermostable green
fluorescent protein. Environ Microbiol 14: 779-793.
Lassak, K., Neiner,
T., Ghosh, A., Klingl, A., Wirth, R., and Albers,
S.V. (2012) Molecular analysis of the crenarchaeal flagellum. Mol
Microbiol 83: 110-124.
Koerdt, A.,
Jachlewski, S., Ghosh, A., Wingender, J., Siebers, B., and Albers,
S.V. (2012) Complementation of Sulfolobus solfataricus PBL2025
with an alpha-mannosidase: effects on surface attachment and biofilm
formation. Extremophiles 16: 115-125.
Ray, R., Ghosh,
A., Bera, A., Dutta, N., Chattopadhyay, D.J., and Chakrabarti,
K. (2011) Analysis of differentially expressed transcripts in
jute upon fungal infection and beta-amino butyric acid treatment. Physiol
Mol Plant Physiol 76: 59-66.
Ghosh, A., Hartung, S., van der Does, C., Tainer, J.A.,
and Albers, S.V. (2011) Archaeal flagellar ATPase motor shows
ATP-dependent hexameric assembly and activity stimulation by specific lipid
binding. Biochem J 437: 43-52.
Basu, S., Roy,
A., Ghosh, A., Bera, A., Chattopadhyay, D., and Chakrabarti,
K. (2011) Arg(235) is an essential catalytic residue of Bacillus pumilus DKS1
pectate lyase to degum ramie fibre. Biodegradation 22:
153-161.
Ghosh, A., Dey, N., Bera, A., Tiwari, A.,
Sathyaniranjan, K., Chakrabarti, K., and Chattopadhyay,
D. (2010) Culture independent molecular analysis of bacterial
communities in the mangrove sediment of Sundarban, India. Saline
Systems 6:1.
Ghosh, A., Chakrabarti, K., and Chattopadhyay,
D. (2009) Cloning of feather-degrading minor extracellular protease
from Bacillus cereus DCUW: dissection of the structural
domains. Microbiology 155: 2049-2057.
Barua, S., Tripathi,
S., Ghosh, A., Chakraborty, A., Ghosh, S., and Chakrabarti,
K. (2008) Studies on Non-symbiotic Diazotropic Bacterial
Population of the saline Soils of Sundarbans. J Pure Appl Microbiol 2:
355-364.
Ghosh, A., Chakrabarti, K., and Chattopadhyay,
D. (2008) Degradation of raw feather by a novel high
molecular weight extracellular protease from newly isolated Bacillus
cereus DCUW. J Ind Microbiol Biotechnol 35:
825-834.
Basu, S., Ghosh,
A., Bera, A., Saha, M.N., Chattopadhyay, D., and Chakrabarti,
K. (2008) Thermodynamic characterization of a
highly thermoactive extracellular pectate lyase from a new
isolate Bacillus pumilus DKS1. Bioresource
Technology 99: 8088-8094.
Sinan, M., Panda,
M., Ghosh, A., Dhara, K., Fanwick, P.E., Chattopadhyay, D.J., and
Goswami, S. (2008) Mild synthesis of a family of
planar triazinium cations via proton-assisted cyclization of pyridyl
containing azo compounds and studies on DNA intercalation. J
American Chem Soc 130: 5185-5193.
Saha, B., Singh,
A.K., Ghosh, A., and Bal, M. (2008) Identification
and characterization of a vancomycin-resistant Staphylococcus aureus isolated
from Kolkata (South Asia). J Med Microbiol 57: 72-79.
Ghosh, A., Basu, S., Datta, H., and Chattopadhyay,
D. (2007) Evaluation of polymerase chain reaction-based
ribosomal DNA Sequencing technique for the diagnosis of mycotic
keratitis. Am J Ophthalmol 144: 396-403.
Ghosh, A., Maity, B., Chakrabarti, K., and Chattopadhyay, D. (2007) Bacterial diversity of east calcutta wet land area: Possible identification of potential bacterial population for different biotechnological uses. Microb Ecol 54: 452-459.
Review articles:
Roy, M, Bhakta, K, Ghosh,
A*. (2022) Minimal Yet Powerful: The Role of Archaeal Small Heat Shock
Proteins in Maintaining Protein Homeostasis. Front. Mol. Biosci.,
9:832160 https://doi.org/10.3389/fmolb.2022.832160
Bhattacharyya, S.,
Sharma, P., Mitra, S., Mallick, I., Ghosh, A. (2021) Arsenic
uptake and bioaccumulation in plants: A review on remediation and
socio-economic perspective in Southeast Asia. Env. Nanotech
Montoring Management 15:100430.
Haldar, S.,
& Ghosh, A*. (2020) Microbial and plant-assisted heavy
metal remediation in aquatic ecosystems: a comprehensive review. 3
Biotech 10:1-13.
Gupta, S., Roy, M.,
and Ghosh, A*. (2017) The Archaeal Signal Recognition
Particle: Present Understanding and Future Perspective. Current
microbiology 74:284-297.
Mahanty, T.,
Bhattacharjee, S., Goswami, M., Bhattacharyya, P., Das, B., Ghosh, A.,
and Tribedi, P. (2016) Biofertilizers: a potential approach for
sustainable agriculture development. Environ Sci Pol Res Int 24: 3315–3335. (doi:
10.1007/s11356-016-8104-0)
Lassak, K., Ghosh,
A., and Albers, S.V. (2012) Diversity, assembly and regulation of
archaeal type IV pili-like and non-type-IV pili-like surface structures. Res
Microbiol 163: 630-644.
Pohlschroder,
M., Ghosh, A., Tripepi, M., and Albers,
S.V. (2011) Archaeal type IV pilus-like structures-evolutionarily
conserved prokaryotic surface organelles. Curr Opin Microbiol 14:
357-363.
Ghosh, A., and Albers, S.V. (2011) Assembly
and function of the archaeal flagellum. Biochem Soc Trans 39:
64-69.
Book Chapters:
Haldar, S, Mondal, S,
Kumari, A, Ghosh, A, Chattopadhyay, D, Ghosh, A*. (2021)
Rhizosphere microbiome engineering. In Ashok Pandey (eds.), Designer
Microbial Cell Factories: Metabolic Engineering and Applications. (2023)
Haldar, S, Kumari, A,
Ghosh, A, Ghosh, A*. (2020) Influence of Biotic and Abiotic
Stresses on Quinoa Cultivation: Insights into Microbe Assisted Stress
Tolerance. In Ajit K. Varma (eds.), Biology and Biotechnology of
Quinoa. January 2022
Bhattacharyya, C, Roy, R, Tribedi, P, Ghosh, A, Ghosh, A*. (2020) Biofertilizers
as substitute to commercial agrochemicals. In M.N.V. Prasad (eds.), Agrochemicals
Detection, Treatment and Remediation, Pesticides and Chemical Fertilizers,
January 2020, 263-290 (ISBN 978-0-081-03017-2).
https://www.elsevier.com/books/agrochemicals-detection-treatment-and-remediation/prasad/978-0-08-103017-2
Mukherji, S, Haldar, S, Ghosh, A*. (2019) Investigation of the Structural and Functional Microbial Diversity in Indian Mangroves. B. Giri, A. Varma (eds.), Microorganisms in Saline Environments: Strategies and Functions, Soil Biology, July 2019, 56: 93-130 (ISBN 978-3-030-18974-7). https://link.springer.com/chapter/10.1007/978-3-030-18975-4_5
Mallick, I, Ghosh,
A, Ghosh, A*. (2019) Microbe-Mediated Removal of Heavy
Metals for Sustainable Agricultural Practices. B. Giri et al. (eds.), Biofertilizers
for Sustainable Agriculture and Environment, Soil Biology, August
2019, 55: 521-544 (ISBN 978-3-030-18932-7).
Dutta, P., Mallick,
I., Ghosh, A., and Basu, M. (2018) Study of Some Predominant
Arsenic Resistance Bacteria from Soil Samples of Industrial Zones of West
Bengal, India. Utilization and Management of Bioresources,
by Springer Publisher Inc., January,
pp: 195-208 (ISBN:978-981-10-5349-8).
Ghosh, A and Chattopadhyay, D.J. (2011)
Feather-degrading enzymes and their prospective applications. Advances
in Bioprocesses in Food Industries, Vol IV by Soccol et. al. published
by AsiaTech Publisher Inc. (ISBN: 9788187680284)
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Recognition:
- Recipient of Carl Storm International Diversity Fellowship for attending the Gordon Research Conferences: Structural, Functional, and Evolutionary Genomics at Wellcome Trust Conference Centre, Hinxton, Cambridge, United Kingdom, 2007
- Recipient of FEMS Congress Grant for Young Scientists from Federation of European Microbiological Society (FEMS) at the 4th FEMS Congress of European Microbiologists at PALEXPO, Geneva, Switzerland, 2011
- Recipient of Max Planck Postdoctoral Fellowship , 2008-2012
- Selected as UGC-Assistant Professor through UGC-Faculty Recharge Program (UGC-FRP) by University Grant Commission (UGC), 2012
- Selected as the Ramanujan Fellow by Department of Science and Technology (DST), India, 2013
- Recipient of DST-Fast Track Scheme for Young Scientists, 2014
- Recipient of EMBO travel grant to attend EMBO workshop on “Molecular biology of archaea: From mechanisms to ecology” at the University of Vienna, Austria, 2018
- Recipient of IGSTC (Indo German Science and Technology Centre) grant to attend Indo-German bilateral workshop on “Agricultural Management Practice Effects on Soil- And Plant-associated bacterial communities and their resistome” at Leibniz Institute of Agricultural Engineering and Bio-economy e.V. (ATB), Potsdam, Germany, 2022
- Recipient of Vigyan Sera Protiva award in the VIGYAN UTSOV organized by Central Calcutta Science & Culture Organisation for Youth (CCSCOY) in co-operation with the Department Of Science & Technology And Biotechnology, Govt of West Bengal , 2022
Teaching:
Bose Institute (MSc--‐PhD): Biophysical techniques (Chromatography), Prokaryotic Molecular Biology; Department of Genetics, Calcutta University (M Sc): Prokaryotic genetics; Bose Institute, Kolkata (PhD coursework): Biophysical techniques (Chromatography).
Students:
| Image | Name | Designation | Department | Campus | Contact number | |
|---|---|---|---|---|---|---|
 |
Agnita Acharya | Junior Research Fellow | Biochemistry | Unified | acharyatheagnita@gmail.com | |
|
Jagriti Das | Junior Research Fellow | Biochemistry | Unified | jagridas85@gmail.com | |
 |
Koustav Bhakta | Senior Research Fellow | Biochemistry | Centenary | koustavb@jcbose.ac.in | |
|
Sangita Mondal | Senior Research Fellow | Biochemistry | Centenary | sangisangita96@gmail.com | |
|
Shirsha Samanta | Junior Research Fellow | Biochemistry | Unified | samantashirsha07@gmail.com |
Postdoctoral Fellows / RA :
| Image | Name | Designation | Department | Campus | Contact number | |
|---|---|---|---|---|---|---|
|
Dhruba Bhattacharya | SERB-NPDF | Biochemistry | Unified | bhattacharya.dhruba95@gmail.com |
Former:
1. Dr.
Ivy Mallick (Commissioning Editor, Springer Nature Group, Netherlands)
2. Dr.
Somi Patranabis (Assistant Professor, Amity University, Kolkata, India)
3. Dr.
Dhritiman Dey (Postdoc at University of Toledo, USA)
4. Dr.
Anish Bhattacharyya (Postdoc at the University of Manchester, United Kingdom)
5. Dr. Mousam Roy (Material Technologists at Unilever UK)
6. Dr. Sayandeep Gupta (Postdoc at University of Oregon, USA)
7. Dr. Shayantan Mukherji (Research Scientist, Reliance Industries Ltd., Mumbai, India)
8. Dr. Chandrima Bhattacharyya (Postdoc at MIGAL Galilee Research Institute, Qiryat Shemona, Northern Israel)
9. Dr. Triparna Mukherjee (Assistant Professor, Brainware
University, Kolkata, India)
Group News:
Openings:
PhD: Positions are presently available for students willing to pursue
PhD in area of microbial genomics/ microbial stress response. Candidates who
have secured fellowships through NET or any other equivalent examination can
send their CV along with a cover letter to aghosh78@gmail.com
RA/Postdoc: Candidates willing to carry out postdoctoral research in the area of the microbial stress response with experience on haloarchaea may go through our research profile and can contact directly by email to Dr. Abhrajyoti Ghosh at aghosh78@gmail.com. We encourage candidates to apply for DBT RA, ICMR RA, SERB-NPDF etc.
We are presently looking for postdoctoral candidates having experience in genomic/ metagenomic and transcriptomic analysis. Interested candidates may contact directly to Dr. Abhrajyoti Ghosh at aghosh78@gmail.com.
News and updates:
30/01/2023: We welcome our new lab member Ms. Shirsha Samanta who will be working in the Biochemistry section of our lab as a UGC-JRF. 01/02/2023 – 30/04/2023: Mr. Arghya Bhowmick visited the laboratory of Prof. Sonja Verena Albers at the University of Freiburg, Germany as a short-term EMBO fellow for collaborative experimental research work.
16/04/2023: It is with a bittersweet sentiment that we bid farewell to our esteemed alumni Dr. Chandrima Bhattacharyya as she embarks on a new journey as a post-doctoral fellow at the MIGAL Galilee Research Institute, Qiryat Shemona, Northern Israel.
21/07/2023: We congratulate our alumni Dr. Mousam Roy as he joined Unilever UK as an enzymologist.
21/07/2023-28/07/2023: Mr. Arghya Bhowmick received the prestigious Carl Storm Inernational Diversity Grant for presenting a poster on “The role of chromosomal type II Toxin- Antitoxin system in the cross-stress adaptation of Sulfolobus acidocaldarius” in the GRS and GRC on Archaea, organized at Mount Snow, West Dover, Vermont, USA.
27/07/2023: The biochemistry group has published a paper entitled “Heat shock response in Sulfolobus acidocaldarius and first implications for cross-stress adaptation” in the journal: Research in Microbiology.
28/11/2023: Mr. Arghya Bhowmick presented a poster and gave a lecture on the topic “Unlocking the secrets of archaeal stress adaptation: insights from Type II Toxin-Antitoxin systems in Sulfolobus acidocaldarius” at the student symposium held on the occasion of 107 th foundation day of Bose Institute.